Evidence map›Paper›PMID 26167450›Full record

ReviewAnalytical cellular pathology (Amsterdam)2015

Significance of circulating tumor cells in soft tissue sarcoma.

Chiara Nicolazzo, Angela Gradilone

Open access · goldAbstract readReview
In one paragraph

Review in Analytical cellular pathology (Amsterdam), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma.Analytical cellular pathology (Amsterdam) · 2018
    Article
  9. Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells.Journal of visualized experiments : JoVE · 2017
    Article
  10. Phenotype of circulating tumor cell: face-off between epithelial and mesenchymal masks.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chiara NicolazzoDipartimento Medicina Molecolare, Sapienza Università di Roma, Viale Regina Elena 324, 00161 Roma, Italy.
Angela GradiloneDipartimento Medicina Molecolare, Sapienza Università di Roma, Viale Regina Elena 324, 00161 Roma, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating tumor cells can be detected from the peripheral blood of cancer patients. Their prognostic value has been established in the last 10 years for metastatic colorectal, breast, and prostate cancer. On the contrary their presence in patients affected by sarcomas has been poorly investigated. The discovery of EpCAM mRNA expression in different sarcoma cell lines and in a small cohort of metastatic sarcoma patients supports further investigations on these rare tumors to deepen the importance of CTC isolation. Although it is not clear whether EpCAM expression might be originally present on tumor sarcoma cells or acquired during the mesenchymal-epithelial transition, the discovery of EpCAM on circulating sarcoma cells opens a new scenario in CTC detection in patients affected by a rare mesenchymal tumor.

Indexed as

Epithelial-Mesenchymal TransitionHumansNeoplastic Cells, CirculatingSarcoma

Identifiers

PMID26167450
PMCPMC4488514
OpenAlexW1527155861

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.