Evidence map›Paper›PMID 26167283›Full record

ArticleJournal of materials chemistry. B2015

Photoelectric artefact from optogenetics and imaging on microelectrodes and bioelectronics: New Challenges and Opportunities.

Takashi D Y Kozai, Alberto L Vazquez

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 159 citations in OpenAlex.

  1. Article
  2. Review
  3. Fabrication of High-Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Multimodal Layer-Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. In vivo microelectrode arrays for neuroscience.Nature reviews. Methods primers · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Journal of neural engineering · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Takashi D Y KozaiDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA. ; McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA. ; Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Alberto L VazquezDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA. ; McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA. ; Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA 15260, USA. ; Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15260, USA.
McGowan Institute for Regenerative Medicine · US

Funding

Improving chronic neural recording performance through biomaterial strategiesR01NS062019 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CUI, XINYAN TRACY · 2008 to 2018
$4.4M
Functional relationship between neural, metabolic and hemodynamic responsesK01NS066131 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VAZQUEZ, ALBERTO L · 2010 to 2014
$617k
NINDS NIH HHS K01 NS066131NINDS NIH HHS R01 NS062019
6 · The paper itself

Abstract

Bioelectronics, electronic technologies that interface with biological systems, are experiencing rapid growth in terms of technology development and applications, especially in neuroscience and neuroprosthetic research. The parallel growth with optogenetics and in vivo multi-photon microscopy has also begun to generate great enthusiasm for simultaneous applications with bioelectronic technologies. However, emerging research showing artefact contaminated data highlight the need for understanding the fundamental physical principles that critically impact experimental results and complicate their interpretation. This review covers four major topics: 1) material dependent properties of the photoelectric effect (conductor, semiconductor, organic, photoelectric work function (band gap)); 2) optic dependent properties of the photoelectric effect (single photon, multiphoton, entangled biphoton, intensity, wavelength, coherence); 3) strategies and limitations for avoiding/minimizing photoelectric effects; and 4) advantages of and applications for light-based bioelectronics (photo-bioelectronics).

Identifiers

PMID26167283
PMCPMC4494685
OpenAlexW2027390911

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.