ReviewFrontiers in immunology2015
Eph/Ephrins-Mediated Thymocyte-Thymic Epithelial Cell Interactions Control Numerous Processes of Thymus Biology.
Review in Frontiers in immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Review
- Thymus Ontogeny and Development.Advances in experimental medicine and biology · 2025Review
- Peripheral T-cell responses of EphB2- and EphB3-deficient mice in a model of collagen-induced arthritis.Cellular and molecular life sciences : CMLS · 2024Article
- Review
- Altered thymocyte development observed in EphA4-deficient mice courses with changes in both thymic epithelial and extracellular matrix organization.Cellular and molecular life sciences : CMLS · 2022Article
- Ephrin Receptors (Ephs) Expression in Thymic Epithelial Tumors: Prognostic Implications and Future Therapeutic Approaches.Diagnostics (Basel, Switzerland) · 2021Article
- How Many Thymic Epithelial Cells Are Necessary for a Proper Maturation of Thymocytes?Frontiers in immunology · 2021Review
- Review
- Eph/ephrin Signaling and Biology of Mesenchymal Stromal/Stem Cells.Journal of clinical medicine · 2020Review
- Changes in ephrin gene expression during bone healing identify a restricted repertoire of ephrins mediating fracture repair.Histochemistry and cell biology · 2019Article
- Can a Proper T-Cell Development Occur in an Altered Thymic Epithelium? Lessons From EphB-Deficient Thymi.Frontiers in endocrinology · 2018Article
- Altered Maturation of Medullary TEC in EphB-Deficient Thymi Is Recovered by RANK Signaling Stimulation.Frontiers in immunology · 2018Article
- EphB receptors, mainly EphB3, contribute to the proper development of cortical thymic epithelial cells.Organogenesis · 2017Article
- Increased epithelial-free areas in thymuses with altered EphB-mediated thymocyte-thymic epithelial cell interactions.Histochemistry and cell biology · 2017Article
- In focus in HCB.Histochemistry and cell biology · 2017Article
- A review on Eph/ephrin, angiogenesis and lymphangiogenesis in gastric, colorectal and pancreatic cancers.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2017Article
- Truncated EphA2 likely potentiates cell adhesion via integrins as well as infiltration and/or lodgment of a monocyte/macrophage cell line in the red pulp and marginal zone of the mouse spleen, where ephrin-A1 is prominently expressed in the vasculature.Histochemistry and cell biology · 2017Article
- Eph/ephrin-B-mediated cell-to-cell interactions govern MTS20(+) thymic epithelial cell development.Histochemistry and cell biology · 2016Article
- Editorial: The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance.Frontiers in immunology · 2015Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous studies emphasize the relevance of thymocyte-thymic epithelial cell (TECs) interactions for the functional maturation of intrathymic T lymphocytes. The tyrosine kinase receptors, Ephs (erythropoietin-producing hepatocyte kinases) and their ligands, ephrins (Eph receptor interaction proteins), are molecules known to be involved in the regulation of numerous biological systems in which cell-to-cell interactions are particularly relevant. In the last years, we and other authors have demonstrated the importance of these molecules in the thymic functions and the T-cell development. In the present report, we review data on the effects of Ephs and ephrins in the functional maturation of both thymic epithelial microenvironment and thymocyte maturation as well as on their role in the lymphoid progenitor recruitment into the thymus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.