Evidence map›Paper›PMID 26167084›Full record

Observational studyWorld journal of gastroenterology2015

Seroepidemiology of hepatitis B virus infection and impact of vaccination.

Peng Huang, Li-Guo Zhu, Ye-Fei Zhu, Ming Yue, Jing Su, Feng-Cai Zhu, Hai-Tao Yang, Yun Zhang, Hong-Bing Shen, Rong-Bin Yu and 2 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  17. Screening and diagnosis of HBV in low-income and middle-income countries.Nature reviews. Gastroenterology & hepatology · 2016
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Peng HuangPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Li-Guo ZhuPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Ye-Fei ZhuPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Ming YuePeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Jing SuPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Feng-Cai ZhuPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Hai-Tao YangPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Yun ZhangPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Hong-Bing ShenPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Rong-Bin YuPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Xiang-Jun ZhaiPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Zhi-Hang PengPeng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China.
Cancer Research And Biostatistics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate hepatitis B virus (HBV) prevalence in the general population in China.

methodsA total of 148931 individuals were investigated by multistage random sampling in Eastern China. Data were collected on demographics and hepatitis B vaccination history, and serum was tested for hepatitis B surface antigen (HBsAg) by ELISA.

resultsA total of 11469 participants (7.70%, 95%CI: 7.57%-7.84%) were positive for HBsAg. HBsAg prevalence was 0.77% among children < 5 years old but increased progressively from adolescents (1.40%-2.55%) to adults (5.69%-11.22%). A decrease in HBsAg prevalence was strongly associated with vaccination and familial history of HBV among both children and adult groups. Meanwhile, HBsAg risk in adults was associated with invasive testing and sharing needles. The HBV immunization rate among participants aged < 20 years was 93.30% (95%CI: 93.01%-93.58%). Significant difference in HBsAg prevalence appeared between vaccinated and unvaccinated participants (3.59% vs 10.22%).

conclusionAlthough the national goal of HBsAg prevalence < 1% among children < 5 years old has been reached, immunization programs should be maintained to prevent resurgence.

Indexed as

VaccinationAdolescentAdultAgedAge DistributionAge FactorsBiomarkersChildChild, PreschoolChinaFemaleHepatitis BHepatitis B Surface AntigensHepatitis B VaccinesHepatitis B virusHumansBiomarkersHepatitis B Surface AntigensHepatitis B VaccinesEpidemiological studyFamilial historyGeneral populationHepatitis B surface antigenImmunization

Identifiers

PMID26167084
PMCPMC4491971
OpenAlexW2395921820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.