ArticleJournal of neurosciences in rural practice
Clinical spectrum and radiographic features of the syndrome of the trephined.
Article in Journal of neurosciences in rural practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 41 citations in OpenAlex.
- Syndrome of the trephined: from pathophysiology to cranioplasty - an updated narrative review.Brain & spine · 2026Review
- Sunken flap following chest tube placement in the presence of ventriculopleural shunt: a case report.Journal of medical case reports · 2024Article
- Article
- Recent Updates on Controversies in Decompressive Craniectomy and Cranioplasty: Physiological Effect, Indication, Complication, and Management.Korean journal of neurotrauma · 2023Review
- Impact of Cranioplasty on Rehabilitation Course of Patients with Traumatic or Hemorrhagic Brain Injury.Brain sciences · 2022Article
- Current Concepts in Cranial Reconstruction: Review of Alloplastic Materials.Plastic and reconstructive surgery. Global open · 2022Article
- Unusual presentation in syndrome of trephined - A unique case observation.Surgical neurology international · 2022Article
- Sinking skin syndrome in a decompressive craniectomy series: Clinical and radiological features.Surgical neurology international · 2022Article
- The Trendelenburg Test: Simple Method to Avoid Wound Healing Complications after Cranioplasty.Plastic and reconstructive surgery. Global open · 2019Article
- Bioinspired Collagen Scaffolds in Cranial Bone Regeneration: From Bedside to Bench.Advanced healthcare materials · 2017Review
- The syndrome of the trephined.Journal of neurosciences in rural practiceArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectCraniectomy is a common neurosurgical procedure. Syndrome of the trephined (ST) occurring after craniectomy results in neurologic symptoms that are reversible with cranioplasty. While well-documented, previous literature consisted of case reports, symptom spectrum and risk factors have not been well characterized. MATERIALS AND
methodsA retrospective review of 29 consecutive cases who underwent decompressive craniectomy within a 30-month period was performed. Patients were considered affected by ST if a previously stable neurological deficit improved within 3 weeks after cranioplasty. Prevalence of ST was measured and association with demographic information, clinical symptoms patterns, indication for and size of craniectomy, as well as radiological signs were tested.
resultsSeven patients (24%) developed ST. Chronic rehabilitation arrest was more common than acute neurologic decline. Factors such as craniectomy size and patient age did not reach statistical significance in development of ST. Radiographic factors were predictive, with a sunken skin flap contour being most sensitive, while ventricular effacement was most specific.
conclusionST may have a higher incidence than previously thought, with a chronic rehabilitation arrest being a more common presentation than an acute decline. Medical providers involved in the post surgical care and rehabilitation of these patients should maintain a high index of suspicion for ST.
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