Evidence map›Paper›PMID 26166119›Full record

ArticleMedicine2015

Primary Multiple Pulmonary Primitive Neuroectodermal Tumor: Case Report and Literature Review.

Ming Dong, Jinghao Liu, Zuoqing Song, Xin Li, Tao Shi, Dan Wang, Dian Ren, Jun Chen

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. A rare radiotherapy-sensitive primitive neuroectodermal tumor withThe Journal of international medical research · 2022
    Review
  3. Peripheral primitive neuroectodermal tumor: a case report.Journal of medical case reports · 2022
    Article
  4. Article
  5. Article
  6. Primary pulmonary Ewing sarcoma/peripheral primitive neuroectodermal tumor.Proceedings (Baylor University. Medical Center) · 2020
    Article
  7. Primary Ewing's sarcoma of the lung: a rare case report.Indian journal of thoracic and cardiovascular surgery · 2020
    Article
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ming DongFrom the Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute (MD, JL, ZS, XL, DR, JC); Department of Pathology; Tianjin Medical University General Hospital, Heping District, Tianjin, China (TS, DW).
Jinghao Liu
Zuoqing Song
Xin Li
Tao Shi
Dan Wang
Dian Ren
Jun Chen
Creative Commons · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primitive neuroectodermal tumors (PNETs) arising directly from the lung are extremely rare but particularly aggressive neoplasms. Although thoracic PNET usually develops on the chest wall, there have been reports of primary Ewing sarcoma/PNET of the lung.We present the case of a 16-year-old male with PNET diagnosed following histologic and immunohistochemical examination of a video-assisted thoracic surgical biopsy. As typically occurring for these tumors, the diagnosis was initially delayed in our patient and prognosis was poor despite aggressive surgical resection and postoperative chemotherapy. We attempted to explore the use of targeted pharmacotherapy through high-throughput sequencing in this case. We found that this treatment using Avastin and Cetuximab could provide a new therapeutic direction for PNET.PNENTs arising from the lung parenchyma without pleural or chest wall involvement are extremely rare. Although uncommon, if the pathological features are similar to Ewing sarcoma, PNENTs should be kept in mind, and the target therapy may be a potent treatment for this disease.

Indexed as

AdolescentHumansLung NeoplasmsMaleMutationNeuroectodermal Tumors, PrimitivePrognosisTomography, X-Ray Computed

Identifiers

PMID26166119
PMCPMC4504587
OpenAlexW2228660906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.