Evidence map›Paper›PMID 26164767›Full record

ArticleAmerican journal of infection control2015

Control of norovirus outbreak on a pediatric oncology unit.

Anna Sheahan, Gretchen Copeland, Lauren Richardson, Shelley McKay, Alexander Chou, N Esther Babady, Yi-Wei Tang, Farid Boulad, Janet Eagan, Kent Sepkowitz and 1 more

Abstract read
In one paragraph

Article in American journal of infection control, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2021
    Article
  6. Prospective, Real-time Metagenomic Sequencing During Norovirus Outbreak Reveals Discrete Transmission Clusters.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
  7. Article
  8. Update on infection control practices in cancer hospitals.CA: a cancer journal for clinicians · 2018
    Review
  9. Article
  10. Review
  11. Norovirus in Transplantation.Current infectious disease reports · 2016
    Review
  12. Infection Prevention in Transplantation.Current infectious disease reports · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anna SheahanInfection Control Program and Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: anna.e.dow@gmail.com.
Gretchen CopelandInfection Control Program and Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Lauren RichardsonInfection Control Program and Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Shelley McKayDepartment of Pediatric Nursing, Memorial Sloan Kettering Cancer Center, New York, NY.
Alexander ChouPediatric Oncology and Bone Marrow Transplant Service, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.
N Esther BabadyClinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Yi-Wei TangClinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Farid BouladPediatric Oncology and Bone Marrow Transplant Service, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.
Janet EaganInfection Control Program and Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Kent SepkowitzInfection Control Program and Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Mini KambojInfection Control Program and Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundPatients undergoing treatment for cancer with chemotherapy and hematopoietic stem cell recipients are at risk for severe morbidity caused by norovirus (NV).

methodsWe describe a NV outbreak on the Memorial Sloan Kettering Cancer Center's pediatric oncology unit. Stool testing for diagnosis of NV was performed by real-time polymerase chain reaction (PCR).

resultsTwelve NV cases occurred; 7 were hospital acquired. Twenty-five health care workers reported NV compatible illness. Patient-to-patient transmission occurred once. The practices of the Centers for Disease Control and Prevention were supplemented with electronic surveillance, surrogate screening for NV, and heightened cleaning. Two additional cases occurred after implementation of interventions. Long-term shedding was detected in 2 patients.

conclusionWe describe interventions for controlling NV on a pediatric oncology unit. High-risk chronic shedders pose ongoing transmission risks. PCR is a valuable diagnostic tool but may be overly sensitive. Surrogate markers to assess NV burden in stool and studies on NV screening are needed to develop guidelines for high-risk chronic shedders.

Indexed as

Disease OutbreaksOncology Service, HospitalAdolescentAdultCaliciviridae InfectionsChildChild, PreschoolCross InfectionDisease Transmission, InfectiousFecesFemaleHospitals, PediatricHumansInfantInfection ControlMaleImmunocompromisedMolecular diagnosticsNorovirusOutbreakPediatric

Identifiers

PMID26164767
PMCPMC4988230

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.