ReviewCurrent hypertension reports2015
Influence of vascular function and pulsatile hemodynamics on cardiac function.
Review in Current hypertension reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Carotid energy pulsatility index provides complementary hemodynamic information to renal function in a community-based cohort.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Interrelations of aortic spring function, cardiovascular disease risk factors, and left ventricular diastolic function: The Framingham Heart Study.Physiological reports · 2026Article
- Aortic stretch and recoil create wave-pumping effect: the second heart in the systemic circulation.Journal of the Royal Society, Interface · 2025Article
- Mechanistic insights on age-related changes in heart-aorta-brain hemodynamic coupling using a pulse wave model of the entire circulatory system.American journal of physiology. Heart and circulatory physiology · 2023Article
- On the Longitudinal Wave Pumping in Fluid-filled Compliant Tubes.Physics of fluids (Woodbury, N.Y. : 1994) · 2023Article
- Heart Failure with Preserved Left Ventricular Ejection Fraction: A Complex Conundrum Simply Not Limited to Diastolic Dysfunction.Cardiovascular therapeutics · 2023Review
- Aortic Stiffness and Pulsatile Pressures as Potential Mediators of Chronic Kidney Disease Induced Impaired Diastolic Function.International journal of nephrology and renovascular disease · 2022Article
- Article
- Age-related values of aortic pulse wave velocity in healthy subjects measured by Doppler echocardiography.Journal of human hypertension · 2021Article
- Aortic root movement correlation with the function of the left ventricle.Scientific reports · 2021Article
- Review
- Female Heart Health: Is GPER the Missing Link?Frontiers in endocrinology · 2019Review
- Aortic stiffness, pressure and flow pulsatility, and target organ damage.Journal of applied physiology (Bethesda, Md. : 1985) · 2018Review
- Measurement Repeatability of Central and Peripheral Blood Pressures: The ARIC Study.American journal of hypertension · 2017Article
- Hydraulic forces contribute to left ventricular diastolic filling.Scientific reports · 2017Article
- Aortic stiffening precedes onset of heart failure with preserved ejection fraction in patients with asymptomatic diastolic dysfunction.BMC cardiovascular disorders · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Interactions between cardiac and vascular structure and function normally are optimized to ensure delivery of cardiac output with modest pulsatile hemodynamic overhead. Aortic stiffening with age or disease impairs optimal ventricular-vascular coupling, increases pulsatile load, and contributes to left ventricular (LV) hypertrophy, reduced systolic function, and impaired diastolic relaxation. Aortic pulse pressure and timing of peak systolic pressure are well-known measures of hemodynamic ventricular-vascular interaction. Recent work has elucidated the importance of direct, mechanical coupling between the aorta and the heart. LV systolic contraction results in displacement of aortic and mitral annuli, thereby producing longitudinal stretch in the ascending aorta and left atrium, respectively. Force associated with longitudinal stretch increases systolic load on the LV. However, the resulting energy stored in the elastic elements of the proximal aorta during systole facilitates early diastolic LV recoil and rapid filling. This review discusses current views on hemodynamics and mechanics of ventricular-vascular coupling.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.