Evidence map›Paper›PMID 26163818›Full record

ArticlePsychosomatic medicine

Glycemia, Diabetes Status, and Cognition in Hispanic Adults Aged 55-64 Years.

José A Luchsinger, Rafi Cabral, Joseph P Eimicke, Jennifer J Manly, Jeanne Teresi

Open access · greenAbstract read
In one paragraph

Article in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

José A LuchsingerFrom the Departments of Medicine (Luchsinger, Cabral) and Epidemiology (Luchsinger, Teresi) and Gertrude H. Sergievsky Center (Manly), Columbia University Medical Center, New York, New York; and Research Division (Eimicke), Hebrew Home for the Aged in Riverdale, Bronx, New York.
Rafi Cabral
Joseph P Eimicke
Jennifer J Manly
Jeanne Teresi
Hebrew Home · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
RESEARCH COREP60MD000206 · NIMHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LUCHSINGER, JOSE ALEJANDRO · 2003 to 2012
$16.2M
NCRR NIH HHS UL1 RR024156NCRR NIH HHS UL RR 024156NIMHD NIH HHS P60 MD000206
6 · The paper itself

Abstract

objectivesTo examine the association of glycemia and diabetes status with cognition among 600 Hispanics aged 55 to 64 years from Northern Manhattan.

methodsDiabetes was ascertained by history or hemoglobin A1c. Normal glucose tolerance and prediabetes were ascertained with hemoglobin A1c. Memory was assessed with the Selective Reminding Test. Executive abilities were assessed using the Color Trails 1 and 2 and verbal fluency test. The cross-sectional association of glycemia and diabetes status with cognitive performance was examined using linear regression.

resultsParticipants had a mean age of 59.2 (2.9) years, 76.7% were women, and more than 65% had prediabetes or diabetes. HbA1C (β = -0.97, p < .001) and diabetes (β = -2.06, p = .001) were related with lower Selective Reminding Test total recall after adjustment for demographics, education, and vascular risk factors. Prediabetes was associated with worse performance in Color Trail 2 (β = -6.45 p = .022) after full adjustment.

conclusionsHigher glycemia and diabetes are related to worse memory and executive abilities in late middle age, whereas prediabetes is related only to worse executive abilities. Longitudinal follow-up is needed to understand the order and progression of these deficits.

Indexed as

Cognition DisordersCross-Sectional StudiesDiabetes MellitusExecutive FunctionFemaleGlycated HemoglobinHispanic or LatinoHumansMaleMental RecallMiddle AgedNew York CityPrediabetic StateGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID26163818
PMCPMC4503370
OpenAlexW2416914973

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.