ArticleJournal of experimental botany2015
Two Theobroma cacao genotypes with contrasting pathogen tolerance show aberrant transcriptional and ROS responses after salicylic acid treatment.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 53 citations in OpenAlex.
- Reduced Susceptibility to Phytophthora in Non-Transgenic Cacao Progeny Through CRISPR-Cas9 Mediated TcNPR3 Mutagenesis.Plant biotechnology journal · 2026Article
- Pathogen-specific stomatal responses in cacao leaves to Phytophthora megakarya and Rhizoctonia solani.Scientific reports · 2025Article
- A combination of conserved and diverged responses underlies Theobroma cacao's defense response to Phytophthora palmivora.BMC biology · 2024Article
- Integrative transcriptomics reveals association of abscisic acid and lignin pathways with cassava whitefly resistance.BMC plant biology · 2023Article
- Interactions of Different Species ofMicroorganisms · 2023Review
- Ethylene Promotes Expression of the Appressorium- and Pathogenicity-Related Genes via GPCR- and MAPK-Dependent Manners inJournal of fungi (Basel, Switzerland) · 2022Article
- The effects of the phytochemistry of cocoa on the food chemistry of chocolate(s) and how disease resistance in cocoa can be improved using CRISPR/Cas9 technology.Food chemistry. Molecular sciences · 2021Review
- Clovamide, a Hydroxycinnamic Acid Amide, Is a Resistance Factor AgainstFrontiers in plant science · 2020Article
- Resistant and susceptible cacao genotypes exhibit defense gene polymorphism and unique early responses to Phytophthora megakarya inoculation.Plant molecular biology · 2019Article
- Transient Expression of CRISPR/Cas9 Machinery TargetingFrontiers in plant science · 2018Article
- Article
- Theobroma cacao L. pathogenesis-related gene tandem array members show diverse expression dynamics in response to pathogen colonization.BMC genomics · 2016Article
- Protocol: transient expression system for functional genomics in the tropical tree Theobroma cacao L.Plant methods · 2016Article
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7 authors at 3 institutions in 1 country.
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Abstract
Understanding the genetic basis of pathogen susceptibility in various crop plants is crucial to increasing the stability of food, feed, and fuel production. Varietal differences in defence responses provide insights into the mechanisms of resistance and are a key resource for plant breeders. To explore the role of salicylic acid in the regulation of defence in cacao, we demonstrated that SA treatment decreased susceptibility to a pod rot pathogen, Phytophthora tropicalis in two genotypes, Scavina 6 and Imperial College Selection 1, which differ in their resistance to several agriculturally important pathogens. Transient overexpression of TcNPR1, a major transcriptional regulator of the SA-dependent plant immune system, also increased pathogen tolerance in cacao leaves. To explore further the genetic basis of resistance in cacao, we used microarrays to measure gene expression profiles after salicylic acid (SA) treatment in these two cacao genotypes. The two genotypes displayed distinct transcriptional responses to SA. Unexpectedly, the expression profile of the susceptible genotype ICS1 included a larger number of pathogenesis-related genes that were induced by SA at 24h after treatment, whereas genes encoding many chloroplast and mitochondrial proteins implicated in reactive oxygen species production were up-regulated in the resistant genotype, Sca6. Sca6 accumulated significantly more superoxide at 24h after treatment of leaves with SA. These experiments revealed critical insights regarding the molecular differences between cacao varieties, which will allow a better understanding of defence mechanisms to help guide breeding programmes.
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