ArticleThe Plant cell2015
Aquaporins Contribute to ABA-Triggered Stomatal Closure through OST1-Mediated Phosphorylation.
Article in The Plant cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.
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Who cites it
133 citing papers in PubMed, 306 citations in OpenAlex.
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- Hydraulic Signaling in Plants: From Physical Perturbation to Distributed Perception and Context-Dependent Decoding.Plants (Basel, Switzerland) · 2026Review
- Membrane Proteomics Reveals the Role of Plant-Derived Smoke Solution on Wheat Under Salt Stress.International journal of molecular sciences · 2026Article
- Engineering climate-resilient horticultural crops: advances in transcriptional regulation, genome editing, and synthetic networks.Horticulture research · 2026Article
- Arabidopsis OST1 homologs of barley are involved in stomatal regulation.Journal of experimental botany · 2026Article
- Transcriptome Dynamics Provide Insight into the Mechanisms Underlying Cucumber Stomatal Movement Regulated by Blue Light (BL) and Drought Stress.International journal of molecular sciences · 2026Article
- Dynamic and Basal Phosphorylation Landscapes of Abscisic Acid Signaling Revealed by Phosphoproteome Analysis in Arabidopsis.International journal of molecular sciences · 2026Article
- Transcriptional and post-translational regulation of aquaporins in plants.Stress biology · 2026Review
- Cell wall water shields stomata against falling leaf airspace humidity.The New phytologist · 2026Article
- Guard-cell expression of abscisic acid receptors for engineering water-use-efficient plants without trade-offs in growth.The New phytologist · 2025Article
- Elicitation with CaClPlant cell reports · 2025Article
- Arabidopsis MACP2 contributes to autophagy induction by modulating starvation-induced reactive oxygen species homeostasis.Advanced biotechnology · 2025Article
- Post-translational modification acts as a digital like switch influencing AtPIP2;1 water and cation permeability.Scientific reports · 2025Article
- The maize aquaporin ZmPIP1;6 enhances stomatal opening and CO2- and ABA-induced stomatal closure.Journal of experimental botany · 2025Article
- The Aquaporin MdPIP2;2 Regulates Glomerella Leaf Spot Resistance in Apple.Molecular plant pathology · 2025Article
- Reactive Oxygen Species in Plants: Metabolism, Signaling, and Oxidative Modifications.Antioxidants (Basel, Switzerland) · 2025Review
- SnRK2s: Kinases or Substrates?Plants (Basel, Switzerland) · 2025Review
- Phosphorylation of PIP2;7 by CPK28 or Phytophthora kinase effectors dampens pattern-triggered immunity in Arabidopsis.Plant communications · 2025Article
- Whole Genome Identification and Integrated Analysis of Long Non-Coding RNAs Responding ABA-Mediated Drought Stress inCurrent issues in molecular biology · 2024Article
73 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stomatal movements in response to environmental stimuli critically control the plant water status. Although these movements are governed by osmotically driven changes in guard cell volume, the role of membrane water channels (aquaporins) has remained hypothetical. Assays in epidermal peels showed that knockout Arabidopsis thaliana plants lacking the Plasma membrane Intrinsic Protein 2;1 (PIP2;1) aquaporin have a defect in stomatal closure, specifically in response to abscisic acid (ABA). ABA induced a 2-fold increase in osmotic water permeability (Pf) of guard cell protoplasts and an accumulation of reactive oxygen species in guard cells, which were both abrogated in pip2;1 plants. Open stomata 1 (OST1)/Snf1-related protein kinase 2.6 (SnRK2.6), a protein kinase involved in guard cell ABA signaling, was able to phosphorylate a cytosolic PIP2;1 peptide at Ser-121. OST1 enhanced PIP2;1 water transport activity when coexpressed in Xenopus laevis oocytes. Upon expression in pip2;1 plants, a phosphomimetic form (Ser121Asp) but not a phosphodeficient form (Ser121Ala) of PIP2;1 constitutively enhanced the Pf of guard cell protoplasts while suppressing its ABA-dependent activation and was able to restore ABA-dependent stomatal closure in pip2;1. This work supports a model whereby ABA-triggered stomatal closure requires an increase in guard cell permeability to water and possibly hydrogen peroxide, through OST1-dependent phosphorylation of PIP2;1 at Ser-121.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.