Evidence map›Paper›PMID 26163561›Full record

ArticleCBE life sciences education2015

Authentic Research Experience and "Big Data" Analysis in the Classroom: Maize Response to Abiotic Stress.

Irina Makarevitch, Cameo Frechette, Natalia Wiatros

Abstract read
In one paragraph

Article in CBE life sciences education, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. A Course-Based Research Experience Using the Allen Brain Map: From Research Question to Poster Session.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2021
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  7. Learning How to Code While Analyzing an Open Access Electrophysiology Dataset.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Irina MakarevitchDepartment of Biology, Hamline University, Saint Paul, MN 55104 imakarevitch01@hamline.edu.
Cameo FrechetteDepartment of Biology, Hamline University, Saint Paul, MN 55104.
Natalia WiatrosDepartment of Biology, Hamline University, Saint Paul, MN 55104.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integration of inquiry-based approaches into curriculum is transforming the way science is taught and studied in undergraduate classrooms. Incorporating quantitative reasoning and mathematical skills into authentic biology undergraduate research projects has been shown to benefit students in developing various skills necessary for future scientists and to attract students to science, technology, engineering, and mathematics disciplines. While large-scale data analysis became an essential part of modern biological research, students have few opportunities to engage in analysis of large biological data sets. RNA-seq analysis, a tool that allows precise measurement of the level of gene expression for all genes in a genome, revolutionized molecular biology and provides ample opportunities for engaging students in authentic research. We developed, implemented, and assessed a series of authentic research laboratory exercises incorporating a large data RNA-seq analysis into an introductory undergraduate classroom. Our laboratory series is focused on analyzing gene expression changes in response to abiotic stress in maize seedlings; however, it could be easily adapted to the analysis of any other biological system with available RNA-seq data. Objective and subjective assessment of student learning demonstrated gains in understanding important biological concepts and in skills related to the process of science.

Indexed as

BiologyCold TemperatureComputational BiologyCurriculumEducational MeasurementFemaleGene Expression ProfilingGene Expression Regulation, PlantHumansMaleMolecular BiologyPhenotypeResearchSequence Analysis, RNAStress, PhysiologicalStudents

Identifiers

PMID26163561
PMCPMC4710385

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.