ArticleRheumatology (Oxford, England)2015
Annual consultation incidence of osteoarthritis estimated from population-based health care data in England.
Article in Rheumatology (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05670314 (Molecular Signatures of Endocannabinoid Induced Pain Relief in Humans), which is not on this map. Cited by 43 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Molecular Signatures of Endocannabinoid Induced Pain Relief in Humans: Lifestyle Interventions, Systemic and Localised Changes
Who cites it
43 citing papers in PubMed, 82 citations in OpenAlex.
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- Influence of major trauma and lower limb loss on radiographic progression and incidence of knee osteoarthritis and pain: a comparative and predictive analysis from the ADVANCE study.Arthritis research & therapy · 2026Article
- The effect of early knee symptom on stages of change for exercise and its characteristic among young college students: application of the transtheoretical model.BMC sports science, medicine & rehabilitation · 2026Article
- Knee symptoms among college students and their relationship with physical activity behaviors: a cross-sectional survey.Frontiers in public health · 2026Article
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- Global, regional and national burden of osteoarthritis in 1990-2021: a systematic analysis of the global burden of disease study 2021.BMC musculoskeletal disorders · 2024Article
- Gait analysis of a kinematic retaining implant for Total knee replacements during walking and running.Journal of orthopaedics · 2024Article
- Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis.Molecular medicine reports · 2024Article
- Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50.Scientific reports · 2024Article
- Arthritis prevalence is associated with metabolic syndrome risk factors but not with physical activity in middle-aged and older patients - a cross-sectional study.BMC geriatrics · 2024Article
- Osteoarthritis: pathogenic signaling pathways and therapeutic targets.Signal transduction and targeted therapy · 2023Review
- Effect of Total Hip Arthroplasty with Ceramic Acetabular Component on Clinical, Radiographic and Functional Parameters in Older Patients with Hip Osteoarthritis: Two-Year Follow-Up.Journal of clinical medicine · 2023Article
- Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004 and 2019.Rheumatology advances in practice · 2023Article
- Chronic Low Back Pain with and without Concomitant Osteoarthritis: A Retrospective, Longitudinal Cohort Study of Patients in England.International journal of clinical practice · 2023Observational
- Risk of symptomatic osteoarthritis associated with exposure to ergonomic factors at work in a nationwide Italian survey.International archives of occupational and environmental health · 2023Article
- Prescribing exercise and physical activity to treat and manage health conditions.The Ulster medical journal · 2023Review
- Tetra-primers ARMS-PCR Based Association Analyses of Synonymous and Intronic Variants in the ADAM12 Gene with Susceptibility to Knee Osteoarthritis: A Case-Control Study.Biochemical genetics · 2022Article
- CircTMOD3 promotes lipopolysaccharide-induced chondrocyte apoptosis in osteoarthritis by sponging miR-27a.Journal of bone and mineral metabolism · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo estimate the consultation incidence of OA using population-based health care data in England and compare OA incidence figures with those derived in other countries.
methodsA population-based health care database (Consultations in Primary Care Archive) in England was used to derive the consultation incidence of OA (overall and by joint site) using the maximum available run-in period method. These estimates, and their distribution by age and sex, were compared with those published from population-based health care databases in Canada, the Netherlands and Spain. A novel age-stratified run-in period method was then used to investigate whether the consultation incidence has been increasing over time in younger adults.
resultsThe annual consultation incidence of OA (any joint) was 8.6/1000 persons ≥15 years of age (95% CI 7.9, 9.3) [6.3 (95% CI 5.5, 7.1) in men and 10.8 (95% CI 9.8, 12.0) in women]. Incidence increased sharply between 45 and 64 years of age, peaking at 75-84 years. The joint-specific incidence was 1.4 (95% CI 1.1, 1.7), 3.5 (95% CI 3.1, 3.9) and 1.3 (95% CI 1.1, 1.6) for hip OA, knee OA and hand OA, respectively. The estimates and their distribution by age and sex were broadly consistent with international estimates. Between 2003 and 2010, incidence in those aged 35-44 years increased from 0.3 to 2.0/1000 persons.
conclusionNewly diagnosed cases of OA in England occur in 9 in 1000 at-risk adults each year, similar to other international estimates. Although lower, the consultation incidence proportion in younger adults appears to have increased in the past decade.
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