Evidence map›Paper›PMID 26162604›Full record

ArticleGenome biology2015

Response to: the nature of evidence for and against epigenetic inheritance.

Piroska E Szabó

Abstract readLetterComment
In one paragraph

Article in Genome biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Non-genetic inheritance via the male germline in mammals.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Piroska E SzabóVan Andel Research Institute, Center for Epigenetics, 333 Bostwick Ave, Grand Rapids, MI, 49503, USA. piroska.szabo@vai.org.

Funding

Mechanisms of Genomic ImprintingR01GM064378 · NIGMS · VAN ANDEL RESEARCH INSTITUTE · PI SZABÓ, PIROSKA EDIT · 2002 to 2015
$4.3M
Epigenetic effects if endocrine disruptors in fetal germ cellsR01ES015185 · NIEHS · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI SZABÓ, PIROSKA EDIT · 2006 to 2010
$2.0M
NIEHS NIH HHS R01 ES015185NIGMS NIH HHS R01 GM064378
6 · The paper itself

Abstract

We thank Dr. Nadeau for his interest in our work. Dr. Nadeau has raised concerns about the experimental approach (mouse strains, route of administration, lack of phenotypic assessment) and about the validity of our conclusions. We will respond to each of these concerns point-by point.Please see related article: www.dx.doi.org/10.1186/s13059-015-0709-y.

Indexed as

AnimalsCellular ReprogrammingDNA MethylationEpigenesis, GeneticFemaleGenomic ImprintingMalePregnancy

Identifiers

PMID26162604
PMCPMC4499172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.