Evidence map›Paper›PMID 26162369›Full record

Observational studyBMC nephrology2015

Understanding barriers to optimal medication management for those requiring long-term dialysis: rationale and design for an observational study, and a quantitative description of study variables and data.

Trudi Aspden, Martin J Wolley, Tian M Ma, Edwin Rajah, Samantha Curd, Dharni Kumar, Sophia Lee, Krenare Pireva, Olita Taule'alo, Porsche Tiavale and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Trudi AspdenSchool of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. t.aspden@auckland.ac.nz.
Martin J WolleySchool of Medicine, University of Queensland, 288 Herston Road, Brisbane, 4006, Australia. martin.wolley@gmail.com.
Tian M MaDepartment of Renal Medicine, Counties Manukau District Health Board, Hospital Road, Otahuhu, Auckland, 1640, New Zealand. maggiema.aut@gmail.com.
Edwin RajahMarketing Department, Faculty of Business, Auckland University of Technology, 46 Wakefield St, Auckland, 1010, New Zealand. erajah@aut.ac.nz.
Samantha CurdFormerly of the School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. samlouisecurd@gmail.com.
Dharni KumarFormerly of the School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. dharni_k91@hotmail.com.
Sophia LeeFormerly of the School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. sophia.lee2404@gmail.com.
Krenare PirevaFormerly of the School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. krenny_p@hotmail.com.
Olita Taule'aloFormerly of the School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. olita_85@hotmail.com.
Porsche TiavaleFormerly of the School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. pjtiavale@gmail.com.
Angela L KamPharmacy Services, Counties Manukau District Health Board, Hospital Road, Otahuhu, Auckland, 1640, New Zealand. angela.kam@middlemore.co.nz.
Jun S SuhDepartment of Renal Medicine, Counties Manukau District Health Board, Hospital Road, Otahuhu, Auckland, 1640, New Zealand. junssuh@gmail.com.
Julia KennedySchool of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. julia.kennedy@auckland.ac.nz.
Mark R MarshallSchool of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Rd, Auckland, 1142, New Zealand. mrmarsh@woosh.co.nz.
University of Auckland · NZCounties Manukau District Health Board · NZAuckland University of Technology · NZMiddlemore Hospital · NZThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRates of medication non-adherence in dialysis patients are high, and improving adherence is likely to improve outcomes. Few data are available regarding factors associated with medication adherence in dialysis patients, and these data are needed to inform effective intervention strategies. METHODS/

designThis is an observational cross-sectional study of a multi-ethnic dialysis cohort from New Zealand, with the main data collection tool being an interviewer-assisted survey. A total of 100 participants were randomly sampled from a single centre, with selection stratified by ethnicity and dialysis modality (facility versus home). The main outcome measure is self-reported medication adherence using the Morisky 8-Item Medication Adherence Scale (MMAS-8). Study data include demographic, clinical, social and psychometric characteristics, the latter being constructs of health literacy, medication knowledge, beliefs about medications, and illness perceptions. Psychometric constructs were assessed through the following survey instruments; health literacy screening questions, the Medication Knowledge Evaluation Tool (Okuyan et al.), the Beliefs about Medication Questionnaire (Horne et al.), the Brief Illness Perception Questionnaire (Broadbent et al.). Using the study data, reliability analysis for internal consistency is satisfactory for the scales evaluating health literacy, medication knowledge, and beliefs about medications, with Chronbach's α > 0.7 for all. Reliability analysis indicated poor internal consistency for scales relating to illness perceptions. MMAS-8 and all psychometric scores are normally distributed in the study data. DISCUSSION: This study will provide important information on the factors involved in medication non-adherence in New Zealand dialysis patients. The resulting knowledge will inform long-term initiatives to reduce medication non-adherence in dialysis patients, and help ensure that they are addressing appropriate and evidence based targets for intervention.

Indexed as

Health Knowledge, Attitudes, PracticeHealth LiteracyMedication AdherenceRenal DialysisCohort StudiesCross-Sectional StudiesHumansKidney Failure, ChronicNew ZealandPsychometricsSelf ReportSurveys and QuestionnairesWhite People

Identifiers

PMID26162369
PMCPMC4499205
OpenAlexW1558937030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.