ArticlePloS one2015
Chicken Caecal Microbiome Modifications Induced by Campylobacter jejuni Colonization and by a Non-Antibiotic Feed Additive.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
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Who cites it
83 citing papers in PubMed.
- Early-Life Oat Supplementation Is Associated with Altered Cecal Microbiota and Microbial Metabolic Profiles and ReducedInternational journal of molecular sciences · 2026Article
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- Assessing the impact of phage therapy on growth performance, microbiome and phage specific immune response in chickens.Scientific reports · 2026Article
- Co-inoculation of broilers byMicrobiology spectrum · 2026Article
- Virulence and Immune Response of Campylobacter Jejuni Strains in Chicken Embryo Model.Current microbiology · 2026Article
- Caecal microbiome transplant inhibits transmission and intestinal colonisation ofPoultry science and management · 2026Article
- Effects of exogenous protease supplementation of diets containing animal proteins or not on Campylobacter jejuni colonization and on the intestinal microbiota of broiler chickens.Gut pathogens · 2025Article
- Application of a liposomal subunit vaccine in chickens for reduction ofJournal of veterinary research · 2024Article
- The influence of biotic and abiotic factors on the bacterial microbiome of gentoo penguins (Pygoscelis papua) in their natural environment.Scientific reports · 2024Article
- Combined application of bacteriophages with a competitive exclusion culture and carvacrol with organic acids can reduce Campylobacter in primary broiler production.Scientific reports · 2024Article
- Characterizing the Effect ofAnimals : an open access journal from MDPI · 2024Article
- No colonization resistance toFrontiers in microbiology · 2024Article
- Essential oils mix effect on chicks ileal and caecal microbiota modulation: a metagenomics sequencing approach.Frontiers in veterinary science · 2024Article
- Next-Generation Sequencing for the Detection of Microbial Agents in Avian Clinical Samples.Veterinary sciences · 2023Review
- Prevalence and Association ofMicroorganisms · 2023Article
- Investigation of the Effect of Three Commercial Water Acidifiers on the Performance, Gut Health, andAnimals : an open access journal from MDPI · 2023Article
- Microorganisms Involved in Hydrogen Sink in the Gastrointestinal Tract of Chickens.International journal of molecular sciences · 2023Article
- The Development of Gut Microbiota and Its Changes FollowingVaccines · 2023Review
- Gut microbiota shift in layer pullets fed on black soldier fly larvae-based feeds towards enhancing healthy gut microbial community.Scientific reports · 2022Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Campylobacter jejuni is an important zoonotic foodborne pathogen causing acute gastroenteritis in humans. Chickens are often colonized at very high numbers by C. jejuni, up to 10(9) CFU per gram of caecal content, with no detrimental effects on their health. Farm control strategies are being developed to lower the C. jejuni contamination of chicken food products in an effort to reduce human campylobacteriosis incidence. It is believed that intestinal microbiome composition may affect gut colonization by such undesirable bacteria but, although the chicken microbiome is being increasingly characterized, information is lacking on the factors affecting its modulation, especially by foodborne pathogens. This study monitored the effects of C. jejuni chicken caecal colonization on the chicken microbiome in healthy chickens. It also evaluated the capacity of a feed additive to affect caecal bacterial populations and to lower C. jejuni colonization. From day-0, chickens received or not a microencapsulated feed additive and were inoculated or not with C. jejuni at 14 days of age. Fresh caecal content was harvested at 35 days of age. The caecal microbiome was characterized by real time quantitative PCR and Ion Torrent sequencing. We observed that the feed additive lowered C. jejuni caecal count by 0.7 log (p<0.05). Alpha-diversity of the caecal microbiome was not affected by C. jejuni colonization or by the feed additive. C. jejuni colonization modified the caecal beta-diversity while the feed additive did not. We observed that C. jejuni colonization was associated with an increase of Bifidobacterium and affected Clostridia and Mollicutes relative abundances. The feed additive was associated with a lower Streptococcus relative abundance. The caecal microbiome remained relatively unchanged despite high C. jejuni colonization. The feed additive was efficient in lowering C. jejuni colonization while not disturbing the caecal microbiome.
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