Evidence map›Paper›PMID 26161441›Full record

ArticleACS infectious diseases2015

Unraveling Cholesterol Catabolism in

Meng Yang, Rui Lu, Kip E Guja, Matthew F Wipperman, Johnna R St Clair, Amber C Bonds, Miguel Garcia-Diaz, Nicole S Sampson

Abstract read
In one paragraph

Article in ACS infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The impact ofFrontiers in immunology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Structural Basis of Cyclic 1,3-Diene Forming Acyl-Coenzyme A Dehydrogenases.Chembiochem : a European journal of chemical biology · 2021
    Article
  13. Comparative Analysis of Bile-Salt Degradation inApplied and environmental microbiology · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Post-translational Succinylation ofACS infectious diseases · 2020
    Article
  19. Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Meng YangDepartment of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Rui LuDepartment of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Kip E GujaDepartment of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Matthew F WippermanDepartment of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Johnna R St ClairDepartment of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Amber C BondsDepartment of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Miguel Garcia-DiazDepartment of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Nicole S SampsonDepartment of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Stony Brook University · US

Funding

Case Center for Synchrotron BiosciencesP30EB009998 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI CHANCE, MARK R · 2009 to 2018
$8.4M
Training Program in Pharmacological SciencesT32GM007518 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI GARCIA-DIAZ, MIGUEL · 1985 to 2021
$5.4M
SBU Chemistry-Biology Interface Training ProgramT32GM092714 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI SAMPSON, NICOLE S, TONGE, PETER J · 2010 to 2019
$1.7M
Mechanisms of mitochondrial transcriptionR01GM100021 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI GARCIA-DIAZ, MIGUEL · 2012 to 2016
$1.5M
Steroid Hormone Biosynthesis by M.tbR21AI092455 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI SAMPSON, NICOLE S · 2011 to 2012
$425k
Investigation of Mycobacterial GMC Oxidoreductase Rv3409cR21AI085349 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI SAMPSON, NICOLE S · 2010 to 2011
$422k
MALDI-TOF SPECTROM: PROTEIN: INHIBIT FATTY ACID BIOSYNTHESIS IN M TUBERCULOSISS10RR021008 · NCRR · STATE UNIVERSITY NEW YORK STONY BROOK · PI SAMPSON, NICOLE S. · 2005 to 2005
$270k
Characterization of an essential mitochondrial rRNA methyltransferaseF30ES022930 · NIEHS · STATE UNIVERSITY NEW YORK STONY BROOK · PI GUJA, KIP E · 2013 to 2014
$95k
NCRR NIH HHS S10 RR021008NIAID NIH HHS R21 AI085349NIAID NIH HHS R21 AI092455NIBIB NIH HHS P30 EB009998NIEHS NIH HHS F30 ES022930NIGMS NIH HHS R01 GM100021NIGMS NIH HHS T32 GM007518NIGMS NIH HHS T32 GM092714
6 · The paper itself

Abstract

The metabolism of host cholesterol by

Indexed as

17-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA3-oxo-23,24-bisnorchol-4,17-dien-22-oyl-CoA3-oxo-23,24-bisnorchol-4-en-22-oyl-CoAcholesterol metabolismdrug targettuberculosis

Identifiers

PMID26161441
PMCPMC4489319
OpenAlexW1964733591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.