Evidence map›Paper›PMID 26161434›Full record

ArticleGenes & diseases2014

Lung gene therapy-How to capture illumination from the light already present in the tunnel.

Emily Xia, Manjunatha Ankathatti Munegowda, Huibi Cao, Jim Hu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes & diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emily XiaPhysiology & Experimental Medicine Program, Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 0A4, Canada ; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 0A4, Canada.
Manjunatha Ankathatti MunegowdaPhysiology & Experimental Medicine Program, Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 0A4, Canada ; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 0A4, Canada.
Huibi CaoPhysiology & Experimental Medicine Program, Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 0A4, Canada ; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 0A4, Canada.
Jim HuPhysiology & Experimental Medicine Program, Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 0A4, Canada ; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 0A4, Canada.
University of Toronto · CA

Funding

CIHR 125882-1CIHR 15628-3PHS HHS 125882-1PHS HHS 15628-3
6 · The paper itself

Abstract

Gene therapy has been considered as the most ideal medical intervention for genetic diseases because it is intended to target the cause of diseases instead of disease symptoms. Availability of techniques for identification of genetic mutations and for

Indexed as

Animal modelCystic fibrosisGene therapyLung diseasesVector delivery

Identifiers

PMID26161434
PMCPMC4494836
OpenAlexW2094471889

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.