ArticleAnesthesiology and pain medicine2015
The Effects of Topical Sesame (Sesamum indicum) Oil on Pain Severity and Amount of Received Non-Steroid Anti-Inflammatory Drugs in Patients With Upper or Lower Extremities Trauma.
Article in Anesthesiology and pain medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Alleviating severity of limb trauma pain with coadministration of topical sesame oil and standard treatments: A GRADE-assessed systematic review and meta-analysis of randomised controlled trials.International wound journal · 2024Pooled it
- A quasi-experimental study on conservative nursing measures for preventing phlebitis in chemotherapy patients.Scientific reports · 2025Trial
- Comparing the Effects of Sesame Oil vs. Nitroglycerin Ointment on the Incidence of Chemotherapy-Induced Phlebitis: A Single Blind Clinical Trial.Asian Pacific journal of cancer prevention : APJCP · 2023Trial
- Effect of oral sesame oil gelatin capsules on episiotomy pain in primiparous women: a triple-blind randomized controlled trial.Maternal health, neonatology and perinatology · 2025Article
- Optimal Hydrothermal Treatment of Sesame Seeds to Retain Most of the Nutrients.Plant foods for human nutrition (Dordrecht, Netherlands) · 2023Article
- Effect of Topical Sesame Oil on the Severity of Pain in Patients With Limb Trauma: A Randomized Controlled Trial.Journal of chiropractic medicine · 2022Article
- Effects of Topical Sesame Oil Extracted from Tahini (Bulletin of emergency and trauma · 2020Article
- Clinical Efficacy and Safety of Yellow Oil Formulations 3 and 4 versus Indomethacin Solution in Patients with Symptomatic Osteoarthritis of the Knee: A Randomized Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Promising pain-relieving activity of an ancient Persian remedy (mixture of white Lily in sesame oil) in patients with chronic low back pain.Journal of family medicine and primary care · 2019Article
- An Integrative Approach to Neuroinflammation in Psychiatric disorders and Neuropathic Pain.Journal of experimental neuroscience · 2018Review
- Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils.International journal of molecular sciences · 2017Review
- The Healing Effect of Grape Seed Oil Enema with or without Sesame Oil in Acetic Acid Induced Ulcerative Colitis of Rats.World journal of plastic surgery · 2017Article
- Topical application of medicinal plant oils in pediatric-related disorders: A comparative review article based on traditional Persian medicine.Avicenna journal of phytomedicineReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost patients with trauma experience different levels of pain. Due to side effects as well as economic burden of drugs used for pain relief after trauma commonly, it is important to use low-cost methods independently or combined with drugs to alleviate pain.
objectivesTherefore, this study aimed to investigate the effects of topical sesame oil on pain severity and frequency of received NSAIDs of patients with trauma. PATIENTS AND
methodsThis randomized clinical trial study was conducted on 150 patients with upper or lower extremities trauma in Dezful Ganjavian Hospital, Ahvaz, Iran, in 2014. Data was collected by a researcher-made questionnaire and Visual Analogue Scale (VAS). Patients were divided into two groups of control (n = 75) and intervention (n = 75) randomly. In the intervention group, patients applied topical sesame oil beside the routine cares, while in the control group patients just received routine cares. Severity of pain and frequency of received NSAIDs was assessed in the first, third, seventh and tenth days after the intervention in the both groups. Data was analyzed by SPSS19 software using descriptive and analytic (Chi-square and independent sample t-test) statistical methods.
resultsBased on student sample t-test, there was a significant difference between intervention and control groups regarding the pain severity in the first (P = 0.06), third (P = 0.001), seventh (P = 0.001) and tenth (P = 0.001) days after the intervention. Besides, the frequency of received NSAIDs in the intervention group and the control group showed significant difference in four days after the intervention (for four days P = 0.001).
conclusionsTopical application of sesame oil could reduce pain severity and frequency of received NSAIDs in patients with upper or lower extremities trauma. Therefore, it is recommended to use this oil in complementary medicine for pain relief due to low cost, easy usage and lack of adverse effects.
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