ArticleEvidence-based complementary and alternative medicine : eCAM2015
Antimicrobial Activity of the Essential Oil of Plectranthus neochilus against Cariogenic Bacteria.
Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed.
- Bioactive Compounds ofMolecules (Basel, Switzerland) · 2026Review
- Research progress and antibacterial mechanisms of plant essential oils as alternative therapies for periodontitis.Frontiers in microbiology · 2026Review
- Comprehensive Phytochemical Analysis and Evaluation of Antioxidant, Antimicrobial, Cytotoxic, and Immunomodulatory Activities of Commercial Cinnamon Bark Essential Oil (International journal of molecular sciences · 2025Article
- Antimicrobial Activities of Essential Oils of DifferentPharmaceutics · 2024Article
- LC-MS Characterization and Biological Activities of Cuban Cultivars ofPlants (Basel, Switzerland) · 2022Article
- Nanoemulsion as an Effective Inhibitor of Biofilm-forming Bacterial Associated Drug Resistance: An Insight into COVID Based Nosocomial Infections.Biotechnology and bioprocess engineering : BBE · 2022Review
- Review
- The Essential Oil Composition and Antimicrobial Activity ofPlants (Basel, Switzerland) · 2020Article
- Mosquito Larvicidal Activity, Antimicrobial Activity, and Chemical Compositions of Essential Oils from Four Species of Myrtaceae from Central Vietnam.Plants (Basel, Switzerland) · 2020Article
- Plants and Lactic Acid Bacteria Combination for New Antimicrobial and Antioxidant Properties Product Development in a Sustainable Manner.Foods (Basel, Switzerland) · 2020Article
- Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview.Molecules (Basel, Switzerland) · 2020Review
- Inhibitory Effects of β-Caryophyllene onInternational journal of molecular sciences · 2020Article
- Comparison Study of Different Extracts ofBiomolecules · 2019Article
- Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and biofilm of oxacillin- and vancomycin-resistant Staphylococcus aureus.BMC complementary and alternative medicine · 2017Article
- In Vitro Anti-Cariogenic Plaque Effects of Essential Oils Extracted from Culinary Herbs.Journal of clinical and diagnostic research : JCDR · 2017Article
- Antimicrobial Properties of Plant Essential Oils against Human Pathogens and Their Mode of Action: An Updated Review.Evidence-based complementary and alternative medicine : eCAM · 2016Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work used the broth microdilution method to investigate the antimicrobial activity of the essential oil obtained from the leaves of Plectranthus neochilus (PN-EO) against a representative panel of oral pathogens. We assessed the antimicrobial activity of this oil in terms of the minimum inhibitory concentration (MIC). PN-EO displayed moderate activity against Enterococcus faecalis (MIC = 250 μg/mL) and Streptococcus salivarus (MIC = 250 μg/mL), significant activity against Streptococcus sobrinus (MIC = 62.5 μg/mL), Streptococcus sanguinis (MIC = 62.5 μg/mL), Streptococcus mitis (MIC = 31.25 μg/mL), and Lactobacillus casei (MIC = 31.25 μg/mL), and interesting activity against Streptococcus mutans (MIC = 3.9 μg/mL). GC-FID and GC-MS helped to identify thirty-one compounds in PN-EO; α-pinene (1, 14.1%), β-pinene (2, 7.1%), trans-caryophyllene (3, 29.8%), and caryophyllene oxide (4, 12.8%) were the major chemical constituents of this essential oil. When tested alone, compounds 1, 2, 3, and 4 were inactive (MIC > 4000 μg/mL) against all the microorganisms. These results suggested that the essential oil extracted from the leaves of Plectranthus neochilus displays promising activity against most of the evaluated cariogenic bacteria, especially S. mutans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.