Evidence map›Paper›PMID 26161034›Full record

ArticleEuropean journal of organic chemistry2014

Calixarene-Mediated Liquid-Membrane Transport of Choline Conjugates.

Birendra Babu Adhikari, Ayu Fujii, Michael P Schramm

Open access · greenAbstract read
In one paragraph

Article in European journal of organic chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Birendra Babu AdhikariDepartment of Chemistry and Biochemistry, University Long Beach,, 1250 Bellflower Blvd., Long Beach, CA 90840, USA: http://schrammlab.wordpress.com.
Ayu FujiiDepartment of Chemistry and Biochemistry, University Long Beach,, 1250 Bellflower Blvd., Long Beach, CA 90840, USA: http://schrammlab.wordpress.com.
Michael P SchrammDepartment of Chemistry and Biochemistry, University Long Beach,, 1250 Bellflower Blvd., Long Beach, CA 90840, USA: http://schrammlab.wordpress.com.
California State University, Long Beach · US

Funding

Selective Small Molecule Membrane Transport Using Cavitand ReceptorsSC2CA167636 · NCI · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI SCHRAMM, MICHAEL P · 2011 to 2013
$425k
NCI NIH HHS SC2 CA167636
6 · The paper itself

Abstract

A series of supramolecular calixarenes efficiently transport distinct molecular species through a liquid membrane when attached to a receptor-complementary choline handle. Calix-[6]arene hexacarboxylic acid was highly effective at transporting different target molecules against a pH gradient. Both carboxylic- and phosphonic-acid-functionalized calix[4]arenes effect transport without requiring a pH or ion gradient. NMR binding studies, two-phase solvent extraction, and three-phase transport experiments reveal the necessary and subtle parameters to effect the transport of molecules attached to a choline "handle". On the other hand, rescorin[4]arene cavitands, which have similar guest recognition profiles, did not transport guest molecules. These developments reveal new approaches towards attempting synthetic-receptor-mediated selective small-molecule transport in vesicular and cellular systems.

Indexed as

CalixarenesCavitandsCholine conjugatesHost-guest systemsLiquid-membrane transportMolecular recognition

Identifiers

PMID26161034
PMCPMC4493905
OpenAlexW1910834930

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.