SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2015
Association between alcohol consumption and multiple sclerosis: a meta-analysis of observational studies.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Alcohol consumption is associated with excessive risk of multiple sclerosis: a meta-analysis observational study.Sao Paulo medical journal = Revista paulista de medicinaPooled it
- Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study.Asia Pacific journal of clinical nutrition · 2026Article
- Comorbidity and modifiable risk factors in multiple sclerosis.Therapeutic advances in neurological disorders · 2026Review
- Dietary Inflammatory Score (DIS)'s and Lifestyle Inflammatory Score (LIS)'s Impact on Multiple Sclerosis Severity.Nutrients · 2025Article
- Behavioral disorders in multiple sclerosis: a comprehensive review.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Natural language processing analysis of the theories of people with multiple sclerosis about causes of their disease.Communications medicine · 2024Article
- Causal effects of dietary composition on multiple sclerosis risk and severity: a Mendelian randomization study.Frontiers in nutrition · 2024Article
- Article
- Early-Onset Alcohol Dependence and Multiple Sclerosis: Diagnostic Challenges.International journal of environmental research and public health · 2021Article
- Alcohol Consumption and Risk of Common Autoimmune Inflammatory Diseases-Evidence From a Large-Scale Genetic Analysis Totaling 1 Million Individuals.Frontiers in genetics · 2021Article
- Advances in clinical neurology through the journal "Neurological Sciences" (2015-2016).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Article
- Multiple sclerosis-like diagnosis as a complication of previously treated malaria in an iron and vitamin D deficient Nigerian patient.Metabolic brain disease · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the association between alcohol consumption and multiple sclerosis risk, we performed a systematic literature search of PubMed, EmBase and Web of Science databases for all relevant articles regarding alcohol and multiple sclerosis. Our meta-analysis consisted of 10 studies, including nine case-controls and one cohort study. The odds ratios (OR) of the association between alcohol consumption and multiple sclerosis were 0.92 [95 % confidence interval (CI) 0.73-1.17] overall, 0.91 (95 % CI 0.39-2.41) for prospective study, and 0.92 (95 % CI 0.72-1.19) for retrospective studies. In addition, neither subgroup analyses nor sensitivity analyses showed a substantially change in the pooled OR and 95 % CI. Meta-analysis showed that there is no evidence that alcohol consumption is associated with an increased risk of multiple sclerosis. There may be a potential protective effect of alcohol consumption on MS incidence, however, this trend may not be obvious and should be validated by further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.