ArticleNeuropsychologia2015
Cortical contributions to impaired contour integration in schizophrenia.
Article in Neuropsychologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 51 citations in OpenAlex.
- The link between basic visual processing and higher-level social cognition: Eye gaze perception as a bridge in a transdiagnostic sample enriched with social dysfunction.Psychological medicine · 2026Article
- Impaired Contour Object Perception in Psychosis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Visual integration deficits associated with psychosis are independent of diagnosis.Schizophrenia (Heidelberg, Germany) · 2025Article
- Examining the joint and unique contributions of contour integration and visuospatial memory to altered eye gaze perception in schizophrenia.Schizophrenia research · 2025Article
- Assessing Trial-by-Trial Electrophysiological and Behavioral Markers of Attentional Control and Sensory Precision in Psychotic and Mood Disorders.Schizophrenia bulletin · 2025Article
- Mapping Brain Synergy Dysfunction in Schizophrenia: Understanding Individual Differences and Underlying Molecular Mechanisms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Impaired contour object perception in psychosis.medRxiv : the preprint server for health sciences · 2024Article
- Faster bi-stable visual switching in psychosis.Translational psychiatry · 2024Article
- The psychosis human connectome project: Design and rationale for studies of visual neurophysiology.NeuroImage · 2023Article
- Perceptual Functioning.Current topics in behavioral neurosciences · 2023Article
- Cognitive [Computational] Neuroscience Test Reliability and Clinical Applications for Serious Mental Illness (CNTRaCS) Consortium: Progress and Future Directions.Current topics in behavioral neurosciences · 2023Article
- Cognitive and perceptual impairments in schizophrenia extend to other psychotic disorders but not schizotypy.Schizophrenia research. Cognition · 2022Article
- The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Both unmedicated and medicated individuals with schizophrenia show impairments across a wide array of cognitive and reinforcement learning tasks.Psychological medicine · 2022Article
- Cortical activation abnormalities in bipolar and schizophrenia patients in a combined oddball-incongruence paradigm.European archives of psychiatry and clinical neuroscience · 2021Article
- Pictorial size perception in schizophrenia.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2021Article
- Reduced influence of perceptual context in schizophrenia: behavioral and neurophysiological evidence.Psychological medicine · 2021Article
- Latent Profiles of Cognitive Control, Episodic Memory, and Visual Perception Across Psychiatric Disorders Reveal a Dimensional Structure.Schizophrenia bulletin · 2020Article
- Neural mechanisms underlying visual and auditory processing impairments in schizophrenia: insight into the etiology and implications for tailoring preventive and therapeutic interventions.American journal of translational research · 2020Review
- Structural and Functional Connectivity of Visual Cortex in Schizophrenia and Bipolar Disorder: A Graph-Theoretic Analysis.Schizophrenia bulletin open · 2020Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
objectivesVisual perceptual organization impairments in schizophrenia (SCZ) are well established, but their neurobiological bases are not. The current study used the previously validated Jittered Orientation Visual Integration (JOVI) task, along with fMRI, to examine the neural basis of contour integration (CI), and its impairment in SCZ. CI is an aspect of perceptual organization in which multiple distinct oriented elements are grouped into a single continuous boundary or shape.
methodsOn the JOVI, five levels of orientational jitter were added to non-contiguous closed contour elements embedded in background noise to progressively increase the difficulty in perceiving contour elements as left- or right-pointing ovals. Multi-site fMRI data were analyzed for 56 healthy control subjects and 47 people with SCZ.
resultsSCZ patients demonstrated poorer CI, and this was associated with increased activation in regions involved in global shape processing and visual attention, namely the lateral occipital complex and superior parietal lobules. There were no brain regions where controls demonstrated more activation than patients.
conclusionsCI impairment in this sample of outpatients with SCZ was related to excessive activation in regions associated with object processing and allocation of visual-spatial attention. There was no evidence for basic impairments in contour element linking in the fMRI data. The latter may be limited to poor outcome patients, where more extensive structural and functional changes in the occipital lobe have been observed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.