ArticlePsychiatry research2015
Genes involved in pruning and inflammation are enriched in a large mega-sample of patients affected by Schizophrenia and Bipolar Disorder and controls.
Article in Psychiatry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Linking Inflammation, Aberrant Glutamate-Dopamine Interaction, and Post-synaptic Changes: Translational Relevance for Schizophrenia and Antipsychotic Treatment: a Systematic Review.Molecular neurobiology · 2022Pooled it
- Searching for gene-gene interactions through variance quantitative trait loci of 29 continuous Taiwan Biobank phenotypes.Frontiers in genetics · 2024Article
- Redox and Immune Signaling in Schizophrenia: New Therapeutic Potential.The international journal of neuropsychopharmacology · 2023Review
- Impact of SARS-CoV-2 on Host Factors Involved in Mental Disorders.Frontiers in microbiology · 2022Review
- SARS-CoV-2-associated cytokine storm during pregnancy as a possible risk factor for neuropsychiatric disorder development in post-pandemic infants.Neuropharmacology · 2021Review
- Involvement of the nuclear factor-κB transcriptional complex in prefrontal cortex immune activation in bipolar disorder.Translational psychiatry · 2021Article
- Age effects on basic symptoms in the community: A route to gain new insight into the neurodevelopment of psychosis?European archives of psychiatry and clinical neuroscience · 2020Article
- Basic Symptoms Are Associated With Age in Patients With a Clinical High-Risk State for Psychosis: Results From the PRONIA Study.Frontiers in psychiatry · 2020Article
- Inter-α-inhibitor deficiency in the mouse is associated with alterations in anxiety-like behavior, exploration and social approach.Genes, brain, and behavior · 2019Article
- Errant gardeners: glial-cell-dependent synaptic pruning and neurodevelopmental disorders.Nature reviews. Neuroscience · 2017Review
- Long-term depression-associated signaling is required for an in vitro model of NMDA receptor-dependent synapse pruning.Neurobiology of learning and memory · 2017Article
- Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders.Cellular and molecular life sciences : CMLS · 2016Review
Corrections and comments
- Erratum issuedCorrigendum to "Genes involved in pruning and inflammation are enriched in a large mega-sample of patients affected by schizophrenia and bipolar disorder and controls" [Psychiatry Res. 228 (2015) 945-949].2016 · Marco, Calabrò [corrected to Calabrò, Marco]; Antonio, Drago [corrected to Drago, Antonio]; Antonina, Sidoti [corrected to Sidoti, Antonina]; Alessandro, Serretti [corrected to Serretti, Alessandro]; Concetta, Crisafulli [corrected to Crisafulli, Concett
Authors and funding
10 authors.
Funding
Abstract
A molecular pathway analysis has been performed in order to complement previous genetic investigations on Schizophrenia. 4486 Schizophrenic patients and 4477 controls served as the investigation sample. 3521 Bipolar patients and 3195 controls served as replication sample. A molecular pathway associated with the neuronal pruning activity was found to be enriched in subjects with Schizophrenia compared to controls. HLA-C and HLA-DRA had more SNPs associated with both Schizophrenia and Bipolar Disorder than expected by chance.
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Registered trials
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