Evidence map›Paper›PMID 26159884›Full record

ArticleResearch in developmental disabilities

Comparing social reciprocity in preserved speech variant and typical Rett syndrome during the early years of life.

Gillian S Townend, Katrin D Bartl-Pokorny, Jeff Sigafoos, Leopold M G Curfs, Sven Bölte, Luise Poustka, Christa Einspieler, Peter B Marschik

Open access · greenAbstract readComparative Study
In one paragraph

Article in Research in developmental disabilities. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

Gillian S TownendRett Expertise Centre-GKC, Maastricht University Medical Centre, Maastricht, The Netherlands.
Katrin D Bartl-PokornyInstitute of Physiology, Research Unit iDN - interdisciplinary Developmental Neuroscience, Center for Physiological Medicine, Medical University of Graz, Graz, Austria.
Jeff SigafoosSchool of Education, Victoria University of Wellington, Wellington, New Zealand.
Leopold M G CurfsRett Expertise Centre-GKC, Maastricht University Medical Centre, Maastricht, The Netherlands.
Sven BölteCenter of Neurodevelopmental Disorders (KIND), Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Luise PoustkaDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; Department of Child and Adolescent Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Christa EinspielerInstitute of Physiology, Research Unit iDN - interdisciplinary Developmental Neuroscience, Center for Physiological Medicine, Medical University of Graz, Graz, Austria.
Peter B MarschikInstitute of Physiology, Research Unit iDN - interdisciplinary Developmental Neuroscience, Center for Physiological Medicine, Medical University of Graz, Graz, Austria; Center of Neurodevelopmental Disorders (KIND), Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; BEE-PRI: Brain, Ears & Eyes-Pattern Recognition Initiative, BioTechMed-Graz, Graz, Austria. Electronic address: peter.marschik@medunigraz.at.
Medical University of Graz · ATMaastricht University Medical Centre · NLKarolinska Institutet · SEMedical University of Vienna · ATVictoria University of Wellington · NZ

Funding

Austrian Science Fund FWF P 25241
6 · The paper itself

Abstract

This study compared early markers of social reciprocity in children with typical Rett syndrome (RTT) and in those with the preserved speech variant (PSV) of RTT. Retrospective video analysis of 10 toddlers with typical RTT and five with PSV investigated participants' orientation to their name being called between the ages of 5 and 24 months, prior to their diagnosis. From analysis of the recordings two distinct profiles were apparent. Although response rate was higher in girls with typical RTT than PSV at 5 to 8 months this noticeably reversed from 9 to 12 months onwards. By two years of age there was a markedly higher rate and range of responses from girls with PSV. This study contributes to the delineation of different profiles for the variants of RTT.

Indexed as

Child DevelopmentInterpersonal RelationsRett SyndromeSocial BehaviorChild, PreschoolFemaleHumansInfantRetrospective StudiesVideo RecordingFamily videosHome videosPreserved speech variantResponse to nameRetrospective video analysisRett syndromeSocial awareness

Identifiers

PMID26159884
PMCPMC5951281
OpenAlexW843309481

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.