Evidence map›Paper›PMID 26159713›Full record

ArticleCell host & microbe2015

The Bug Stops Here: Innate Lymphoid Cells in Clostridium difficile Infection.

Erica L Buonomo, William A Petri

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. iMetaOmics · 2025
    Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Erica L BuonomoDepartment of Microbiology, Immunology, and Cancer, University of Virginia, Charlottesville, VA 22908, USA.
William A PetriDepartment of Microbiology, Immunology, and Cancer, University of Virginia, Charlottesville, VA 22908, USA; Department of Medicine, University of Virginia, Charlottesville, VA 22908, USA; Department of Pathology, University of Virginia, Charlottesville, VA 22908, USA. Electronic address: wap3g@virginia.edu.
University of Virginia · US

Funding

INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2M
STRUCTURE/FUNCTION OF E HISTOLYTICA ADHERENCE LECTINR01AI026649 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI PETRI, WILLIAM A · 1989 to 2016
$6.1M
Role of Type 2 Immunity in Innate Protection from C. difficileR01AI124214 · NIAID · UNIVERSITY OF VIRGINIA · PI William A Petri · 2016 to 2026
$5.4M
Role of CREM in Amebic Colitis and Inflammatory Bowel DiseaseR37AI026649 · NIAID · UNIVERSITY OF VIRGINIA · PI William A Petri · 2018 to 2026
$5.0M
The Role of IL-23 in the Pathogenesis of Clostridium difficile InfectionF31AI114203 · NIAID · UNIVERSITY OF VIRGINIA · PI BUONOMO, ERICA L · 2014 to 2015
$52k
NIAID NIH HHS 5F31 AI114203-02NIAID NIH HHS 5R01 AI026649-26NIAID NIH HHS 5T32 AI07496NIAID NIH HHS F31 AI114203NIAID NIH HHS R01 AI124214NIAID NIH HHS R37 AI026649
6 · The paper itself

Abstract

The contribution of the innate immune response to the resolution of Clostridium difficile infection (CDI) remains incompletely defined. In this issue of Cell Host & Microbe, Abt et al. demonstrated that innate lymphoid cells and the effector cytokine IFN-γ are important for recovery from the acute phase of CDI.

Indexed as

Disease ResistanceImmunity, InnateAnimalsClostridioides difficileClostridium InfectionsLymphocyte Subsets

Identifiers

PMID26159713
OpenAlexW1601127809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.