ArticleScientific reports2015
Differential protein folding and chemical changes in lung tissues exposed to asbestos or particulates.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- Organizing Pneumonia in a Patient with Pulmonary Transthyretin Amyloidosis.Internal medicine (Tokyo, Japan) · 2026Article
- Involvement of miR-205-5p in mediating the development of nodular thyroid disease associated with coal worker's pneumoconiosis via pulmonary extracellular vesicles.Frontiers in endocrinology · 2025Article
- Ferritin adsorption onto chrysotile asbestos fibers influences the protein secondary structure.Heliyon · 2024Article
- Asbestos and Iron.International journal of molecular sciences · 2023Review
- Article
- Morphological and lipid metabolism alterations in macrophages exposed to model environmental nanoplastics traced by high-resolution synchrotron techniques.Frontiers in immunology · 2023Article
- Correlative High-Resolution Imaging of Iron Uptake in Lung Macrophages.Analytical chemistry · 2022Article
- Elemental Mapping of Human Malignant Mesothelioma Tissue Samples Using High-Speed LA-ICP-TOFMS Imaging.Analytical chemistry · 2022Article
- Characteristics and Trends of Pneumoconiosis in the Jiangsu Province, China, 2006⁻2017.International journal of environmental research and public health · 2019Article
- Ferruginous bodies resolved by synchrotron XRF in a dog with peritoneal malignant mesothelioma.Environmental science and pollution research international · 2018Article
- Plasma LncRNA-ATB, a Potential Biomarker for Diagnosis of Patients with Coal Workers' Pneumoconiosis: A Case-Control Study.International journal of molecular sciences · 2016Article
Corrections and comments
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Authors and funding
15 authors at 8 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental and occupational inhalants may induce a large number of pulmonary diseases, with asbestos exposure being the most risky. The mechanisms are clearly related to chemical composition and physical and surface properties of materials. A combination of X-ray fluorescence (μXRF) and Fourier Transform InfraRed (μFTIR) microscopy was used to chemically characterize and compare asbestos bodies versus environmental particulates (anthracosis) in lung tissues from asbestos exposed and control patients. μXRF analyses revealed heterogeneously aggregated particles in the anthracotic structures, containing mainly Si, K, Al and Fe. Both asbestos and particulates alter lung iron homeostasis, with a more marked effect in asbestos exposure. μFTIR analyses revealed abundant proteins on asbestos bodies but not on anthracotic particles. Most importantly, the analyses demonstrated that the asbestos coating proteins contain high levels of β-sheet structures. The occurrence of conformational changes in the proteic component of the asbestos coating provides new insights into long-term asbestos effects.
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