ArticleMalaria journal2015
Genetic diversity of Plasmodium vivax in clinical isolates from Bangladesh.
Article in Malaria journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Population Dynamics ofMicroorganisms · 2025Article
- Genetic diversity of theParasite epidemiology and control · 2024Article
- Low Genetic Diversity ofTropical medicine and infectious disease · 2024Article
- Exploring genetic polymorphisms among Plasmodium vivax isolates from the Thai-Myanmar borders using circumsporozoite protein (pvcsp) and ookinete surface protein (pvs25) encoding genes.Parasitology research · 2024Article
- Genetic Diversity ofTropical medicine and infectious disease · 2023Article
- Human behaviour directs household-level exposure to malaria vectors in Bandarban, Bangladesh.Malaria journal · 2022Article
- Genetic Diversity of Circumsporozoite Surface Protein ofPathogens (Basel, Switzerland) · 2022Article
- THE USE OF ARCHIVED GIEMSA-STAINED BLOOD SMEARS AND RDT FOR PCR-BASED GENOTYPING OFAfrican journal of infectious diseases · 2022Article
- Genetic characterization of Plasmodium vivax isolates from Pakistan using circumsporozoite protein (pvcsp) and merozoite surface protein-1 (pvmsp-1) genes as genetic markers.Malaria journal · 2021Article
- Genetic polymorphism and natural selection of circumsporozoite protein in Myanmar Plasmodium vivax.Malaria journal · 2020Article
- Exploration of genetic diversity of Plasmodium vivax circumsporozoite protein (Pvcsp) and Plasmodium vivax sexual stage antigen (Pvs25) among North Indian isolates.Malaria journal · 2019Article
- Evaluation of Plasmodium vivax isolates in Thailand using polymorphic markers Plasmodium merozoite surface protein (PvMSP) 1 and PvMSP3.Parasitology research · 2018Article
- Mapping the stability of malaria hotspots in Bangladesh from 2013 to 2016.Malaria journal · 2018Article
- Plasmodium vivax msp-3α polymorphisms: analysis in the Indian subcontinent.Malaria journal · 2016Article
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6 authors.
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Abstract
backgroundPlasmodium vivax is the second most prevalent human malaria parasite in Bangladesh; however, there are no data of its genetic diversity. Several molecular markers are available where Pvcsp, Pvmsp 1 and Pvmsp 3α are most commonly used for P. vivax genotyping studies. The aim of the study was to investigate the population structure of P. vivax in Bangladesh.
methodsA total of 102 P. vivax-positive blood samples were collected from different malaria-endemic areas in Bangladesh and subsequently analysed for those three genotyping markers. Nested PCR was performed for diagnosis and genotyping analysis followed by PCR-RFLP to detect genetic diversity using Pvcsp, Pvmsp 1 and Pvmsp 3α markers.
resultsAnalysis of Pvcsp showed that the VK210 repeat type was highly prevalent (64.7%, 66/102) compared to VK247 (35.3%, 36/102), although the prevalence of VK247 was higher than other Southeast Asian countries. Analysis of these three genes revealed a diverse, circulating population of P. vivax where a total of ten, 56 and 35 distinct genotypes were detected for Pvcsp, Pvmsp 1 and Pvmsp 3α, respectively.
conclusionThis genotyping observation of P. vivax is the first report from Bangladesh and will provide valuable information for establishing the genotyping methods and circulating genetic variants of these three markers available in Bangladesh.
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