ArticleSleep2015
Diet/Energy Balance Affect Sleep and Wakefulness Independent of Body Weight.
Article in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 31 citations in OpenAlex.
- Effect of Six-Month Diet Intervention on Sleep among Overweight and Obese Men with Chronic Insomnia Symptoms: A Randomized Controlled Trial.Nutrients · 2016Trial
- Trial
- Time Restricted Feeding Mitigates High-Fat-Diet Induced Sleep Disruption and Amplifies NREM Substates.bioRxiv : the preprint server for biology · 2026Article
- Age-Associated Development of Sleep Disturbances inNature and science of sleep · 2026Article
- Association between adherence to Dietary Approach to Stop Hypertension (DASH) diet with sleep quality, sleep duration, inflammation, and oxidative stress among Iranian adults.Journal of translational medicine · 2025Article
- Sleep and circadian rhythm activity alterations during adolescence in a mouse model of neonatal fentanyl withdrawal syndrome.Neuroscience · 2025Article
- Calcium/calmodulin-dependent protein kinase II α and β differentially regulate mammalian sleep.Communications biology · 2025Article
- Association between dietary nutrient intake and sleep disorders in hypertensive patients: a cross-sectional study of NHANES, 2005-2020.Frontiers in nutrition · 2025Article
- Signals of energy availability in sleep: consequences of a fat-based metabolism.Frontiers in nutrition · 2024Review
- The relationship between dietary patterns and insomnia in young women.Neuropsychopharmacology reports · 2023Article
- Many faces of sleep regulation: beyond the time of day and prior wake time.The FEBS journal · 2023Review
- Dieting Behavior Characterized by Caloric Restriction and Relation to Sleep: A Brief Contemporary Review.International journal of environmental research and public health · 2022Review
- Reducing ER stress with chaperone therapy reverses sleep fragmentation and cognitive decline in aged mice.Aging cell · 2022Article
- Association of Dietary Behaviors with Poor Sleep Quality and Increased Risk of Obstructive Sleep Apnea in Korean Military Service Members.Nature and science of sleep · 2022Article
- KLF4 Exerts Sedative Effects in Pentobarbital-Treated Mice.Journal of molecular neuroscience : MN · 2021Article
- Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice.The Journal of clinical investigation · 2020Article
- Adherence to a Dietary Approach to Stop Hypertension (DASH)-Style in Relation to Daytime Sleepiness.Nature and science of sleep · 2020Article
- The leptin sensitizer celastrol reduces age-associated obesity and modulates behavioral rhythms.Aging cell · 2019Article
- The neurobiological basis of sleep: Insights from Drosophila.Neuroscience and biobehavioral reviews · 2018Review
- Restoring Serotonergic Homeostasis in the Lateral Hypothalamus Rescues Sleep Disturbances Induced by Early-Life Obesity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
STUDY
objectivesExcessive daytime sleepiness commonly affects obese people, even in those without sleep apnea, yet its causes remain uncertain. We sought to determine whether acute dietary changes could induce or rescue wake impairments independent of body weight.
designWe implemented a novel feeding paradigm that generates two groups of mice with equal body weight but opposing energetic balance. Two subsets of mice consuming either regular chow (RC) or high-fat diet (HFD) for 8 w were switched to the opposite diet for 1 w. Sleep recordings were conducted at Week 0 (baseline), Week 8 (pre-diet switch), and Week 9 (post-diet switch) for all groups. Sleep homeostasis was measured at Week 8 and Week 9.
participantsYoung adult, male C57BL/6J mice. MEASUREMENTS AND
resultsDifferences in total wake, nonrapid eye movement (NREM), and rapid eye movement (REM) time were quantified, in addition to changes in bout fragmentation/consolidation. At Week 9, the two diet switch groups had similar body weight. However, animals switched to HFD (and thus gaining weight) had decreased wake time, increased NREM sleep time, and worsened sleep/wake fragmentation compared to mice switched to RC (which were in weight loss). These effects were driven by significant sleep/wake changes induced by acute dietary manipulations (Week 8 → Week 9). Sleep homeostasis, as measured by delta power increase following sleep deprivation, was unaffected by our feeding paradigm.
conclusionsAcute dietary manipulations are sufficient to alter sleep and wakefulness independent of body weight and without effects on sleep homeostasis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.