Evidence map›Paper›PMID 26158017›Full record

ArticleNeurophotonics2015

Photonics meets connectomics: case of diffuse, long-range horizontal projections in rat cortex.

Brett A Johnson, Ron D Frostig

Abstract read
In one paragraph

Article in Neurophotonics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brett A JohnsonUniversity of California-Irvine , Department of Neurobiology and Behavior, 2205 McGaugh Hall, Irvine, California 92697, United States.
Ron D FrostigUniversity of California-Irvine , Department of Neurobiology and Behavior, 2205 McGaugh Hall, Irvine, California 92697, United States ; University of California-Irvine , Department of Biomedical Engineering, 3120 Natural Sciences II, Irvine, California 92697, United States ; University of California-Irvine , Center for the Neurobiology of Learning and Memory, 320 Qureshey Research Laboratory, Irvine, California 92697, United States.

Funding

Neurovascular PlasticityR01NS066001 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI FROSTIG, RON D · 2010 to 2014
$2.1M
The Size of a Cortical RepresentationR01NS055832 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI FROSTIG, RON D · 2008 to 2012
$1.6M
NINDS NIH HHS R01 NS055832NINDS NIH HHS R01 NS066001
6 · The paper itself

Abstract

Recent years have seen progress in characterizing connections between different regions of the rodent brain to establish a "connectome." This effort involves systematically collected new data together with tools to characterize network relationships in new and preexisting data. The choices made during data collection, analysis, and display in order to generate these connectomes have emphasized dense, specific connections between cortical regions defined using a priori parcellation schemes that may obscure certain spatial relationships in the data. One example of a pattern of connectivity not clearly evident in these connectomes is a diffusely radiating, apparently nonspecific, border-crossing, long-range horizontal axonal projection that is related to horizontal spreads of evoked activity in the rat cortex. Here, we describe the horizontal projection system and explore evidence for this projection within the connectome data. We consider how the differences in optical and histological methodologies and analyses used for the connectome studies and our own studies lead to different emphases concerning this important horizontal projection pattern.

Indexed as

adeno-associated virusbiotinylated dextran amineconnectomecortexhorizontal axonstractography

Identifiers

PMID26158017
PMCPMC4478784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.