Evidence map›Paper›PMID 26157837›Full record

ArticleACG case reports journal2014

Synchronous Small Cell Neuroendocrine Carcinoma and Adenocarcinoma of the Colon: A Link for Common Stem Cell Origin?

Seth Lipka, Jorge Hurtado-Cordovi, Boris Avezbakiyev, Lester Freedman, Toshimasa Clark, Kaleem Rizvon, Paul Mustacchia

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Embryonic Signaling Pathways Shape Colorectal Cancer Subtypes: Linking Gut Development to Tumor Biology.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Seth LipkaDepartment of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL.
Jorge Hurtado-CordoviDepartment of Hematology-Oncology, Miller School of Medicine, University of Miami, Miami, FL.
Boris AvezbakiyevDepartment of Medicine, Division of Hematology and Oncology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY.
Lester FreedmanDepartment of Pathology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY.
Toshimasa ClarkDepartment of Radiology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY.
Kaleem RizvonDepartment of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY.
Paul MustacchiaDepartment of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY.
Nassau University Medical Center · USNorthwell Health · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synchronous carcinomas have been recognized for over a century, with synchronous primary adenocarcinoma of the colon reported to range from 2-11% of cases involving this type of malignancy. Small cell carcinomas occur frequently with colorectal adenomas; however, despite these reports and a known adenoma-to-carcinoma sequence, scarce literature exists on synchronous colorectal adenocarcinoma and small cell carcinomas. We present a rare cancer of synchronous small cell neuroendocrine carcinomas and discuss a possible link between these two cancers.

Identifiers

PMID26157837
PMCPMC4435290
OpenAlexW2104765207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.