Evidence map›Paper›PMID 26157505›Full record

ArticleInternational archives of otorhinolaryngology2015

Thickened Pituitary Stalk Associated with a Mass in the Sphenoidal Sinus: An Alarm to Suspect Hypophysitis by Immunoglobulin G4?

Rafael Loch Batista, Luciano Silva Ramos, Valter Angelo Cescato, Nina Rosa Castro Musolino, Clarissa Groberio Borba, Gilberto Ochman Silva, Lilian Hupfeld Moreno, Malebranche Bernardo Carneiro Cunha Neto

Open access · diamondAbstract readCase Reports
In one paragraph

Article in International archives of otorhinolaryngology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rafael Loch BatistaNeurosurgical Unit, Universidade de São Paulo, São Paulo, SP, Brazil.
Luciano Silva RamosNeurosurgical Unit, Universidade de São Paulo, São Paulo, SP, Brazil.
Valter Angelo CescatoFuncional Neurosurgery Unit, Universidade de São Paulo, São Paulo, SP, Brazil.
Nina Rosa Castro MusolinoFuncional Neurosurgery Unit, Universidade de São Paulo, São Paulo, SP, Brazil.
Clarissa Groberio BorbaFuncional Neurosurgery Unit, Universidade de São Paulo, São Paulo, SP, Brazil.
Gilberto Ochman SilvaFuncional Neurosurgery Unit, Universidade de São Paulo, São Paulo, SP, Brazil.
Lilian Hupfeld MorenoNeurosurgical Unit, Universidade de São Paulo, São Paulo, SP, Brazil.
Malebranche Bernardo Carneiro Cunha NetoFuncional Neurosurgery Unit, Universidade de São Paulo, São Paulo, SP, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Hypophysitis is a chronic inflammation of the pituitary gland of complex and still incompletely defined pathogenesis. It belongs to the group of non-hormone-secreting sellar masses, sharing with them comparable clinical presentation and radiographic appearance. Objectives Describe the case of immunoglobulin G4 (IgG4)-related hypophysitis presenting as a mass in the sphenoid sinus. Resumed Report A 40-year-old Brazilian man had a diagnosis of central diabetes insipidus since 2001 associated with pituitary insufficiency. Pituitary magnetic resonance imaging revealed a centered pituitary stalk with focal nodular thickening and the presence of heterogeneous materials inside the sphenoid sinus. The patient was treated with testosterone replacement therapy. Laboratory results revealed increased IgG4 serum. Conclusion IgG4-related hypophysitis should be considered in patients with pituitary insufficiency associated with sellar mass and/or thickened pituitary stalk. IgG4 serum measurement for early diagnosis of IgG4-related hypophysitis should be performed.

Indexed as

hypopituitarismpituitary diseasessphenoid sinus

Identifiers

PMID26157505
PMCPMC4490927
OpenAlexW2322536636

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.