Evidence map›Paper›PMID 26157324›Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2015

Comparison of the clinical characteristics and survival between Uyghur patients with hepatitis virus-related and non-B, non-C hepatocellular carcinoma in Xinjiang, China.

Lei Xiao, Rui-Li Zhang, Hua Zhang, Aisiker Tulahong, Yue-Fen Zhang, Hao Wen, Yong-Xing Bao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
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Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lei Xiao1 Cancer Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China ; 2 Key Laboratory of Infection and Cancer, Urumqi 830054, China.
Rui-Li Zhang1 Cancer Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China ; 2 Key Laboratory of Infection and Cancer, Urumqi 830054, China.
Hua Zhang1 Cancer Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China ; 2 Key Laboratory of Infection and Cancer, Urumqi 830054, China.
Aisiker Tulahong1 Cancer Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China ; 2 Key Laboratory of Infection and Cancer, Urumqi 830054, China.
Yue-Fen Zhang1 Cancer Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China ; 2 Key Laboratory of Infection and Cancer, Urumqi 830054, China.
Hao Wen1 Cancer Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China ; 2 Key Laboratory of Infection and Cancer, Urumqi 830054, China.
Yong-Xing Bao1 Cancer Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China ; 2 Key Laboratory of Infection and Cancer, Urumqi 830054, China.
Xinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the clinical characteristics and prognosis between hepatitis virus-related hepatocellular carcinoma (viral HCC) and non-B, non-C HCC (NBC-HCC) among Uyghur patients in Xinjiang province, China.

methodsBetween 01/01/2000 and 31/12/2012, 319 Uyghur HCC patients were treated at the Cancer Centre of The First Affiliated Hospital of Xinjiang Medical University. The data for the patients were obtained from a retrospective review of the patients' medical records. A total of 18 patients were excluded from the study because of incomplete information. The patients were classified into two groups: viral HCC and NBC-HCC. The clinical characteristics and prognostic factors were statistically analysed.

resultsFor all 301 patients, gender (P=0.000), area of residence (P=0.002), diabetes mellitus (P=0.009), BMI (P=0.000), cirrhosis (P=0.000), tumour stage (P=0.004), Child-Pugh class (P=0.000), the TBIL level (P=0.000), and the alpha-fetoprotein (AFP) level (P=0.000) were significantly different between the NBC-HCC and viral HCC groups. The NBC-HCC patients tended to be diagnosed at advanced stages; however, the NBC-HCC patients exhibited lower Child-Pugh scores than the viral HCC patients. In all patients examined, the 0.5-, 1-, 3- and 5-year overall survival (OS) rates were 35.6%, 20.3%, 12.6% and 4.5%, respectively. No significant difference in OS was observed between the two groups (P=0.124). Cox multivariate analysis revealed that age (RR =1.539, P=0.001), TNM stage (RR =12.708, P=0.000), portal vein tumour thrombus (PVTT) (RR =2.003, P=0.000), Child-Pugh class (RR =1.715, P=0.000), and TACE + radiotherapy/RFA (RR =0.567, P=0.000) were significant independent prognostic factors for HCC patients.

conclusionsThe clinical characteristics differ between Uyghur patients with NBC-HCC and viral HCC. HCC in the Xinjiang region displays specific regional characteristics. Age, TNM stage, PVTT, Child-Pugh class and TACE + radiotherapy/RFA are significant risk factors that influence patient survival.

Indexed as

clinical characteristicshepatitis virus-related HCC (viral HCC)Hepatocellular carcinoma (HCC)non-B, non-C HCC (NBC-HCC)Uyghur people

Identifiers

PMID26157324
PMCPMC4490201
OpenAlexW584259500

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.