Evidence map›Paper›PMID 26156870›Full record

ReviewDiagnostic pathology2015

DOME/GALT type adenocarcimoma of the colon: a case report, literature review and a unified phenotypic categorization.

Hala Kannuna, Carlos A Rubio, Patricia Caseiro Silverio, Marc Girardin, Nicolas Goossens, Laura Rubbia-Brandt, Giacomo Puppa

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Diagnostic pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Redefining GALT-associated carcinoma: a distinct subtype of colorectal adenocarcinoma.Virchows Archiv : an international journal of pathology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Colorectal epithelial neoplasm associated with gut-associated lymphoid tissue.Journal of pathology and translational medicine · 2020
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Hala KannunaDepartment of Clinical Pathology, Geneva University Hospital, 1 rue Michel-Servet, 1211, Geneva, Switzerland. Hala.Kannuna@hcuge.ch.
Carlos A RubioDepartment of Pathology, Karolinska University Hospital, Stockholm, Sweden. Carlos.Rubio@ki.se.
Patricia Caseiro SilverioDepartment of Clinical Pathology, Geneva University Hospital, 1 rue Michel-Servet, 1211, Geneva, Switzerland. Patricia.CaseiroSilverio@hcuge.ch.
Marc GirardinDivision of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland. Marc.Girardin@hcuge.ch.
Nicolas GoossensDivision of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland. Nicolas.Goossens@hcuge.ch.
Laura Rubbia-BrandtDepartment of Clinical Pathology, Geneva University Hospital, 1 rue Michel-Servet, 1211, Geneva, Switzerland. Laura.Rubbia-Brandt@hcuge.ch.
Giacomo PuppaDepartment of Clinical Pathology, Geneva University Hospital, 1 rue Michel-Servet, 1211, Geneva, Switzerland. giacomo.puppa@hcuge.ch.
University Hospital of Geneva · CHKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several types of colorectal cancers are associated with a prominent lymphoid component, which is considered a positive prognostic factor. We report a case of a dome-type carcinoma of the cecum in a 57 year old female. The sessile, non-polypoid lesion histologically consisted of a tubulovillous adenoma with low-grade dysplasia. The submucosal invasive component showed low-grade architectural features that included cystically dilated glands containing eosinohilic debris. Immunohistochemical studies displayed retention of the four mistmach repair proteins, consistent with a stable phenotype. After 3 years, the patient remains free of recurrence. A literature review highlighted striking similarities between dome-type carcinoma and the gut-associated lymphoid tissue carcinoma, the two sharing an intimate association with the gut associated lymphoid tissue.The two variants might therefore be grouped into a unified category.

Indexed as

AdenocarcinomaBiomarkers, TumorBiopsyCecal NeoplasmsColectomyColonic NeoplasmsColonoscopyDiagnosis, DifferentialFemaleHumansImmunohistochemistryLymphoid TissueMiddle AgedNeoplasm GradingNeoplasm StagingPhenotypeBiomarkers, Tumor

Identifiers

PMID26156870
PMCPMC4495708
OpenAlexW1534270394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.