ArticleBMC evolutionary biology2015
Sex-specific effects of sympatric mitonuclear variation on fitness in Drosophila subobscura.
Article in BMC evolutionary biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Article
- Mitonuclear effects on sex ratio persist across generations in interpopulation hybrids.Journal of evolutionary biology · 2024Article
- Review
- Mapping mitonuclear epistasis using a novel recombinant yeast population.PLoS genetics · 2023Article
- Temperature-Specific and Sex-Specific Fitness Effects of Sympatric Mitochondrial and Mito-Nuclear Variation inInsects · 2022Article
- Mother's curse is pervasive across a large mitonuclearEvolution letters · 2021Article
- Negative frequency dependent selection contributes to the maintenance of a global polymorphism in mitochondrial DNA.BMC evolutionary biology · 2020Article
- Nutritional geometry of mitochondrial genetic effects on male fertility.Biology letters · 2020Article
- Hybridization, sex-specific genomic architecture and local adaptation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundA number of recent studies have shown that the pattern of mitochondrial DNA variation and evolution is at odds with a neutral equilibrium model. Theory has suggested that selection on mitonuclear genotypes can act to maintain stable mitonuclear polymorphism within populations. However, this effect largely relies upon selection being either sex-specific or frequency dependent. Here, we use mitonuclear introgression lines to assess differences in a series of key life-history traits (egg-to-adult developmental time, viability, offspring sex-ratio, adult longevity and resistance to desiccation) in Drosophila subobscura fruit flies carrying one of three different sympatric mtDNA haplotypes.
resultsWe found functional differences between these sympatric mtDNA haplotypes, but these effects were contingent upon the nuclear genome with which they were co-expressed. Further, we demonstrate a significant mitonuclear genetic effect on adult sex ratio, as well as a sex × mtDNA × nuDNA interaction for adult longevity.
conclusionsThe observed effects suggest that sex specific mitonuclear selection contributes to the maintenance of mtDNA polymorphism and to mitonuclear linkage disequilibrium in this model system.
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