ArticleDiabetes care2015
Cross-sectional and longitudinal associations between objectively measured sedentary time and metabolic disease: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Article in Diabetes care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Pooled it
- Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis.European journal of epidemiology · 2018Pooled it
- Trial
- Associations of nonoccupational sedentary behaviors with cardiometabolic outcomes: coronary artery risk development in young adults (CARDIA).Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025Article
- Daily sampling frequency and sampling duration affect reliability of person-level estimates of physical activity outcomes: Optimizing Ecological Momentary Assessment studies of physical activities.Psychology of sport and exercise · 2024Article
- The association between device-measured sitting time and cardiometabolic health risk factors in children.BMC public health · 2024Article
- Longitudinal association of sedentary time with diabetes mellitus and markers of glucose metabolism in middle-aged and older adults: The Hisayama Study.Journal of diabetes investigation · 2024Article
- Influence of Recent Standing, Moving, or Sitting on Daytime Ambulatory Blood Pressure.Journal of the American Heart Association · 2023Article
- Relationship between Sitting Time and Insulin Resistance in 6931 U.S. Adults: The Mediating Role of Abdominal Adiposity.Journal of diabetes research · 2023Article
- The association between prolonged sedentary time and coronary artery calcification in young healthy men in Korea: a cohort study.Scientific reports · 2022Article
- Article
- Association of the extent of return to fasting state 2-hours after a glucose challenge with incident prediabetes and type 2 diabetes: The CARDIA study.Diabetes research and clinical practice · 2021Article
- Replacement of Sedentary Behavior by Various Daily-Life Physical Activities and Structured Exercises: Genetic Risk and Incident Type 2 Diabetes.Diabetes care · 2021Article
- Sedentary Behavior and Diabetes Risk Among Women Over the Age of 65 Years: The OPACH Study.Diabetes care · 2021Article
- Impact of Self-Reported Sitting Time and Transtheoretical Model Based on Exercise Behavior Change on Glycemic and Weight Control in Japanese Adults with Type 1 Diabetes: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2020Article
- Validity of self-reported and objectively measured sedentary behavior in pregnancy.BMC pregnancy and childbirth · 2020Article
- Associations of sedentary time and self-reported television time during pregnancy with incident gestational diabetes and plasma glucose levels in women at risk of gestational diabetes in the UK.BMC public health · 2019Article
- Objectively measured sedentary time and diabetes mellitus in a general Japanese population: The Hisayama Study.Journal of diabetes investigation · 2019Article
- Stand and Move at Work sedentary behavior questionnaire: validity and sensitivity to change.Annals of epidemiology · 2019Article
- Sedentary Behavior and Prevalent Diabetes in 6,166 Older Women: The Objective Physical Activity and Cardiovascular Health Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveProlonged sedentary time (ST) might be contributing to the diabetes epidemic, but most studies have been cross-sectional and few have objectively measured ST. The purpose of this study was to evaluate cross-sectional and 5-year longitudinal relationships between ST and metabolic parameters and outcomes. RESEARCH DESIGN AND
methodsThis was an analysis of 2,027 Coronary Artery Risk Development in Young Adults (CARDIA) study participants (aged 38-50 years, 57% female, and mean BMI of 29.0 ± 7.0 kg/m(2)) with accelerometry data (≥4 days with ≥10 h/day) measured at the year 20 follow-up exam (2005-2006). Metabolic variables (fasting glucose, fasting insulin, 2-h postchallenge glucose, HOMA of insulin resistance [HOMA-IR], and HbA1c) and outcomes (impaired fasting glucose [IFG], impaired glucose tolerance [IGT], prediabetes by HbA1c, and diabetes) were assessed concurrently and 5 years later.
resultsAverage ST was 8.1 ± 1.7 h/day or 55 ± 10% of wear time. Each additional hour per day of ST was cross-sectionally associated with a 3% higher fasting insulin and HOMA-IR (both P < 0.01) but not 5-year changes in metabolic parameters. Having ≥10 h/day vs. <6 h/day of ST was associated with an odds ratio (OR) = 2.74 (95% CI 1.13, 6.62) for IGT and an OR = 3.80 (95% CI 1.39, 10.35) for diabetes. ST was not associated with prevalent IFG, prevalent prediabetes by HbA1c, or 5-year incidence of any metabolic outcomes (all P > 0.05).
conclusionsST was independently related to insulin, HOMA-IR, and prevalent diabetes and IGT but did not predict 5-year changes in metabolic parameters or incidence of metabolic outcomes. These results suggest that higher ST may not be a risk factor for future metabolic outcomes, but more research with repeated ST measurement and longer follow-up is needed.
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