ArticleGenetics2015
The Genetic Basis of Composite Spike Form in Barley and 'Miracle-Wheat'.
Article in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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Who cites it
76 citing papers in PubMed.
- Auxin-related regulation of barley floral organ fate: genetic and phenotypic insights from tweaky spike mutants.The New phytologist · 2026Article
- Characterization and Fine Mapping ofPlants (Basel, Switzerland) · 2026Article
- COMPOSITUM 2/ WHEAT FRIZZY PANICLE dosage dependently regulates inflorescence and root architecture in Triticeae cereals.The Plant journal : for cell and molecular biology · 2026Article
- Spatial transcriptomics identifies distinct domains regulating yield-component traits of the wheat ear.Science advances · 2026Article
- Grass inflorescence morphodynamics guides yield improvement in wheat.Nature plants · 2026Article
- Regulation of spikelet number during wheat spike development.bioRxiv : the preprint server for biology · 2026Article
- Spatial transcriptomics reveals expression gradients in developing wheat inflorescences at cellular resolution.The Plant cell · 2026Article
- Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development.Nature plants · 2026Article
- Article
- BS-D275: A novel locus on the chromosome arm 2DS governing branched spike development in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Spatial and single-cell expression analyses reveal complex expression domains in early wheat spike development.Genome biology · 2025Article
- Natural variation in CHELATASE SUBUNIT I-A increases grain weight and enhances wheat yield.The Plant cell · 2025Article
- How meristems shape plant architecture in cereals-Cereal Stem Cell Systems (CSCS) Consortium.The Plant cell · 2025Review
- CLAVATA signalling shapes barley inflorescence by controlling activity and determinacy of shoot meristem and rachilla.Nature communications · 2025Article
- Article
- Article
- Fine mapping and candidate gene mining of QSc/Sl.cib-7H for spike compactness and length and its pleiotropic effects on yield-related traits in barley (Hordeum vulgare L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genome-wide dissection of genes shaping inflorescence morphology in 242 Chinese south-north sorghum accessions.Scientific reports · 2024Article
- Identification, validation and candidate gene analysis of major QTL for Supernumerary spikelets in wheat.BMC genomics · 2024Article
- Photoperiod-1 regulates the wheat inflorescence transcriptome to influence spikelet architecture and flowering time.Current biology : CB · 2024Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
26 authors.
Funding
Abstract
Inflorescences of the tribe Triticeae, which includes wheat (Triticum sp. L.) and barley (Hordeum vulgare L.) are characterized by sessile spikelets directly borne on the main axis, thus forming a branchless spike. 'Compositum-Barley' and tetraploid 'Miracle-Wheat' (T. turgidum convar. compositum (L.f.) Filat.) display noncanonical spike-branching in which spikelets are replaced by lateral branch-like structures resembling small-sized secondary spikes. As a result of this branch formation 'Miracle-Wheat' produces significantly more grains per spike, leading to higher spike yield. In this study, we first isolated the gene underlying spike-branching in 'Compositum-Barley,' i.e., compositum 2 (com2). Moreover, we found that COM2 is orthologous to the branched head(t) (bh(t)) locus regulating spike branching in tetraploid 'Miracle-Wheat.' Both genes possess orthologs with similar functions in maize BRANCHED SILKLESS 1 (BD1) and rice FRIZZY PANICLE/BRANCHED FLORETLESS 1 (FZP/BFL1) encoding AP2/ERF transcription factors. Sequence analysis of the bh(t) locus in a collection of mutant and wild-type tetraploid wheat accessions revealed that a single amino acid substitution in the DNA-binding domain gave rise to the domestication of 'Miracle-Wheat.' mRNA in situ hybridization, microarray experiments, and independent qRT-PCR validation analyses revealed that the branch repression pathway in barley is governed through the spike architecture gene Six-rowed spike 4 regulating COM2 expression, while HvIDS1 (barley ortholog of maize INDETERMINATE SPIKELET 1) is a putative downstream target of COM2. These findings presented here provide new insights into the genetic basis of spike architecture in Triticeae, and have disclosed new targets for genetic manipulations aiming at boosting wheat's yield potential.
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