ArticleIntensive care medicine2015
Recovery from AKI in the critically ill: potential confounders in the evaluation.
Article in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 52 citations in OpenAlex.
- Kidney and blood pressure sequelae after pediatric extracorporeal membrane oxygenation: a secondary analysis of the Kidney Injury During Membrane Oxygenation pediatric ECMO cohort.Pediatric nephrology (Berlin, Germany) · 2026Observational
- Baseline and 7-Day Dynamic Changes of T Helper 17/Regulatory T Cells Ratio and Their Association with Renal Recovery and Prognosis in Sepsis-Induced Acute Kidney Injury: An Exploratory Analysis.Infection and drug resistance · 2026Article
- Assessing renal recovery after acute kidney injury in elderly patients: a retrospective cohort study.Renal failure · 2025Article
- Acute Kidney Injury in Patients With Cirrhosis and Chronic Kidney Disease: Results From the HRS-HARMONY Consortium.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025Article
- Chemerin attenuates acute kidney injury by inhibiting ferroptosis via the AMPK/NRF2/SLC7A11 axis.Communications biology · 2024Article
- Associations between fluid overload and outcomes in critically ill patients with acute kidney injury: a retrospective observational study.Scientific reports · 2023Observational
- Prediction model of renal function recovery for primary membranous nephropathy with acute kidney injury.BMC nephrology · 2022Article
- Duration of acute kidney injury predicts 90-day mortality and chronic kidney disease progression in elderly patients.Journal of intensive medicine · 2022Article
- Effect of ondansetron on reducing ICU mortality in patients with acute kidney injury.Scientific reports · 2021Article
- Association of early hypotension in pediatric sepsis with development of new or persistent acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2021Article
- Analysis of the short-term prognosis and risk factors of elderly acute kidney injury patients in different KDIGO diagnostic windows.Aging clinical and experimental research · 2020Article
- Clinical predictors of renal non-recovery in acute respiratory distress syndrome.BMC nephrology · 2019Article
- Low-energy extracorporeal shock wave ameliorates ischemic acute kidney injury in rats.Clinical and experimental nephrology · 2019Article
- Association between serum levels of interleukin-6 on ICU admission and subsequent outcomes in critically ill patients with acute kidney injury.BMC nephrology · 2019Article
- Does acute kidney disease following primary percutaneous coronary intervention lead to chronic kidney disease development and progression?Coronary artery disease · 2019Article
- ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients.Annals of intensive care · 2018Article
- Hypothesis: early renal replacement therapy increases mortality in critically ill patients with acute on chronic renal failure. A post hoc analysis of the AKIKI trial.Intensive care medicine · 2018Article
- Short-term renal outcomes following acute kidney injury among dengue patients: A follow-up analysis from large prospective cohort.PloS one · 2018Article
- Acute kidney injury in the ICU: from injury to recovery: reports from the 5th Paris International Conference.Annals of intensive care · 2017Review
- A nephrologist should be consulted in all cases of acute kidney injury in the ICU: yes.Intensive care medicine · 2017Article
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4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStudies on recovery from acute kidney injury (AKI) in ICU patients yield variable results. We assessed the impact of different recovery definitions, of different exclusion criteria, and of imputing missing baseline creatinine on AKI recovery in a heterogeneous ICU population.
methodsSecondary analysis of the EPaNIC database. Recovery of kidney function in patients who developed AKI in ICU was assessed at hospital discharge. We studied recovery rates of different AKI stages with different definitions of recovery after inclusion or exclusion of non-survivors and in patients with or without chronic kidney disease (CKD). In addition, the impact of imputing missing baseline creatinine was investigated.
resultsA total of 1310 AKI patients were studied of which 977 were discharged alive from hospital. Rate of complete recovery (absence of KDIGO criteria) was markedly higher in survivors than in all AKI patients (79.5 vs 67.0%), especially for more severe forms of AKI. For patients with CKD, only the need for renal replacement therapy worsened kidney outcome as compared with no-CKD patients. Using stricter definitions of complete recovery significantly reduced its occurrence. New or worsening CKD occurred in 30% of AKI survivors. In no-CKD patients with available baseline creatinine, using an imputed baseline did not affect recovery. Patients with unavailable baseline creatinine were different from those with known baseline and revealed different recovery patterns.
conclusionThese results indicate the need for rigorous description of AKI severity, the included population, definitions, and baseline creatinine handling in reports on AKI recovery.
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