ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2016
Prognostic value of coronary computed tomography angiography in diabetic patients without chest pain syndrome.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- The impact of baseline calcified plaque volume on coronary rapid plaque progression by serial coronary computed tomography angiography in patients with type 2 diabetes.Annals of medicine · 2023Article
- Coronary Atherosclerosis Across the Glycemic Spectrum Among Asymptomatic Adults: The Miami Heart Study at Baptist Health South Florida.Circulation. Cardiovascular imaging · 2023Article
- Prognostic Value of Coronary Calcium Score in Asymptomatic Individuals: A Systematic Review.Journal of clinical medicine · 2022Review
- Cardiovascular disease in type 1 diabetes.Cardiovascular endocrinology & metabolism · 2019Review
- Progression of coronary atherosclerotic plaque burden and relationship with adverse cardiovascular event in asymptomatic diabetic patients.BMC cardiovascular disorders · 2019Article
- The complex principle of cause and effect.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Cardiovascular PET/MR imaging: Quo Vadis?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Review
- Review of Cardiovascular Imaging in the Journal of Nuclear Cardiology in 2016. Part 1 of 2: Positron Emission Tomography, Computed Tomography and Magnetic Resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Review
- Imaging Atherosclerosis in Diabetes: Current State.Current diabetes reports · 2016Review
- Non-invasive imaging in assessment of the asymptomatic diabetic patient: Is it of value?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Review of cardiovascular imaging in the journal of nuclear cardiology in 2015. Part 1 of 2: Plaque imaging, positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Review
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10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsDiabetic patients with coronary artery disease (CAD) are often free of chest pain syndrome. A useful modality for non-invasive assessment of CAD is coronary computed tomography angiography (CTA). However, the prognostic value of CAD on coronary CTA in diabetic patients without chest pain syndrome is relatively unknown. Therefore, the aim was to investigate the long-term prognostic value of coronary CTA in a large population diabetic patients without chest pain syndrome.
methodsBetween 2005 and 2013, 525 diabetic patients without chest pain syndrome were prospectively included to undergo coronary artery calcium (CAC)-scoring followed by coronary CTA. During follow-up, the composite endpoint of all-cause mortality, non-fatal myocardial infarction (MI), and late revascularization (>90 days) was registered.
resultsIn total, CAC-scoring was performed in 410 patients and coronary CTA in 444 patients (431 interpretable). After median follow-up of 5.0 (IQR 2.7-6.5) years, the composite endpoint occurred in 65 (14%) patients. Coronary CTA demonstrated a high prevalence of CAD (85%), mostly non-obstructive CAD (51%). Furthermore, patients with a normal CTA had an excellent prognosis (event-rate 3%). An incremental increase in event-rate was observed with increasing CAC-risk category or coronary stenosis severity. Finally, obstructive (50-70%) or severe CAD (>70%) was independently predictive of events (HR 11.10 [2.52;48.79] (P = .001), HR 15.16 [3.01;76.36] (P = .001)). Obstructive (50-70%) or severe CAD (>70%) provided increased value over baseline risk factors.
conclusionCoronary CTA provided prognostic value in diabetic patients without chest pain syndrome. Most importantly, the prognosis of patients with a normal CTA was excellent.
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