Evidence map›Paper›PMID 26156016›Full record

ReviewCirculation. Cardiovascular imaging2015

Noninvasive Imaging of Atherosclerotic Plaque Progression: Status of Coronary Computed Tomography Angiography.

Veit Sandfort, Joao A C Lima, David A Bluemke

Abstract readReview
In one paragraph

Review in Circulation. Cardiovascular imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. The Role of Cardiac Computed Tomography Angiography in Risk Stratification for Coronary Artery Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Coronary Plaque in Athletes.Journal of clinical medicine · 2024
    Review
  16. Review
  17. Review
  18. Article
  19. Diagnostics of atherosclerosis: Overview of the existing methods.Frontiers in cardiovascular medicine · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Veit SandfortFrom the Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD (V.S., D.A.B.); and Department of Radiology (J.A.C.L.) and Cardiology Division, Department of Medicine (J.A.C.L.), Johns Hopkins University, Baltimore, MD.
Joao A C LimaFrom the Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD (V.S., D.A.B.); and Department of Radiology (J.A.C.L.) and Cardiology Division, Department of Medicine (J.A.C.L.), Johns Hopkins University, Baltimore, MD.
David A BluemkeFrom the Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD (V.S., D.A.B.); and Department of Radiology (J.A.C.L.) and Cardiology Division, Department of Medicine (J.A.C.L.), Johns Hopkins University, Baltimore, MD. bluemked@cc.nih.gov.

Funding

Molecular Biomedical Imaging Laboratory (NIBIB)ZIAEB000072 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI BLUEMKE, DAVID · 2010 to 2017
$5.0M
Molecular Biomedical Imaging Laboratory (CC)ZIACL090019 · CLC · CLINICAL CENTER · PI JONES, ELIZABETH C. · 2010 to 2017
$0k
CLC NIH HHS ZIA CL090019-04Intramural NIH HHS ZIA CL090019Intramural NIH HHS ZIA EB000072NIBIB NIH HHS ZIA EB000072-04
6 · The paper itself

Abstract

The process of coronary artery disease progression is infrequently visualized. Intravascular ultrasound has been used to gain important insights but is invasive and therefore limited to high-risk patients. For low-to-moderate risk patients, noninvasive methods may be useful to quantitatively monitor plaque progression or regression and to understand and personalize atherosclerosis therapy. This review discusses the potential for coronary computed tomography angiography to evaluate the extent and subtypes of coronary plaque. Computed tomographic technology is evolving and image quality of the method approaches the level required for plaque progression monitoring. Methods to quantify plaque on computed tomography angiography are reviewed as well as a discussion of their use in clinical trials. Limitations of coronary computed tomography angiography compared with competing modalities include limited evaluation of plaque subcomponents and incomplete knowledge of the value of the method especially in patients with low-to-moderate cardiovascular risk.

Indexed as

Plaque, AtheroscleroticTomography, X-Ray ComputedCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDisease ProgressionHumansMagnetic Resonance AngiographyPredictive Value of TestsPrognosisRisk FactorsSeverity of Illness IndexUltrasonography, Interventionalatherosclerosiscoronary artery diseaseinflammationmyocardial infarctionplaque, atherosclerotic

Identifiers

PMID26156016
PMCPMC4499869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.