Evidence map›Paper›PMID 26155950›Full record

ArticleBreast cancer research : BCR2015

Can the breast screening appointment be used to provide risk assessment and prevention advice?

D Gareth Evans, Anthony Howell

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Breast cancer research : BCR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02619123 (Tailored Screening for Breast Cancer in Premenopausal Women. A Translational, Randomized Population-based Trial), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02619123 naunknown statusnot on this map

Tailored Screening for Breast Cancer in Premenopausal Women. A Translational, Randomized Population-based Trial

TypeinterventionalSponsorCancer Prevention and Research Institute, ItalyRan2013 to 2022Enrolled33,200ConditionsBreast CancerArmsTailored screening according to breast density, Annual invitation to mammography
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  3. A novel preclinical model of the normal human breast.Journal of mammary gland biology and neoplasia · 2024
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  13. Calibrated Breast Density Measurements.Academic radiology · 2019
    Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

D Gareth EvansGenesis Breast Cancer Prevention Centre, University Hospital of South Manchester NHS Trust, Southmoor Road, Wythenshawe, Manchester, M23 9LT, UK. gareth.evans@cmft.nhs.uk.
Anthony HowellGenesis Breast Cancer Prevention Centre, University Hospital of South Manchester NHS Trust, Southmoor Road, Wythenshawe, Manchester, M23 9LT, UK.
The Christie Hospital · GBWythenshawe Hospital · GB

Funding

Department of Health RP-PG-0707-10031
6 · The paper itself

Abstract

Breast cancer risk is continuing to increase across all societies with rates in countries with traditionally lower risks catching up with the higher rates in the Western world. Although cure rates from breast cancer have continued to improve such that absolute numbers of breast cancer deaths have dropped in many countries despite rising incidence, only some of this can be ascribed to screening with mammography, and debates over the true value of population-based screening continue. As such, enthusiasm for risk-stratified screening is gaining momentum. Guidelines in a number of countries already suggest more frequent screening in certain higher-risk (particularly, familial) groups, but this could be extended to assessing risks across the population. A number of studies have assessed breast cancer risk by using risk algorithms such as the Gail model, Tyrer-Cuzick, and BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm), but the real questions are when and where such an assessment should take place. Emerging evidence from the PROCAS (Predicting Risk Of Cancer At Screening) study is showing not only that it is feasible to undertake risk assessment at the population screening appointment but that this assessment could allow reduction of screening in lower-risk groups in many countries to 3-yearly screening by using mammographic density-adjusted breast cancer risk.

Indexed as

Appointments and SchedulesEarly Detection of CancerRisk AssessmentAge FactorsBreast NeoplasmsFemaleHumansMass ScreeningModels, TheoreticalReproducibility of ResultsSurveys and QuestionnairesTime Factors

Identifiers

PMID26155950
PMCPMC4496847
OpenAlexW1759446715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.