Evidence map›Paper›PMID 26155901›Full record

ArticleSocial psychiatry and psychiatric epidemiology2015

Duration of unspecific prodromal and clinical high risk states, and early help-seeking in first-admission psychosis patients.

Frauke Schultze-Lutter, Jonas Rahman, Stephan Ruhrmann, Chantal Michel, Benno G Schimmelmann, Wolfgang Maier, Joachim Klosterkötter

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Article in Social psychiatry and psychiatric epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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36citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  3. Basic symptoms of psychosis-from historical foundations to current evidence.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Frauke Schultze-LutterUniversity Hospital of Child and Adolescent Psychiatry, University of Bern, Bolligenstrasse 111, Haus A, 3000, Bern 60, Switzerland. frauke.schultze-lutter@kjp.unibe.ch.
Jonas RahmanUniversity Hospital of Child and Adolescent Psychiatry, University of Bern, Bolligenstrasse 111, Haus A, 3000, Bern 60, Switzerland.
Stephan RuhrmannDepartment of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.
Chantal MichelUniversity Hospital of Child and Adolescent Psychiatry, University of Bern, Bolligenstrasse 111, Haus A, 3000, Bern 60, Switzerland.
Benno G SchimmelmannUniversity Hospital of Child and Adolescent Psychiatry, University of Bern, Bolligenstrasse 111, Haus A, 3000, Bern 60, Switzerland.
Wolfgang MaierDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
Joachim KlosterkötterDepartment of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrevention of psychosis requires both presence of clinical high risk (CHR) criteria and early help-seeking. Previous retrospective studies of the duration of untreated illness (i.e. prodrome plus psychosis) did not distinguish between prodromal states with and without CHR symptoms. Therefore, we examined the occurrence of CHR symptoms and first help-seeking, thereby considering effects of age at illness-onset.

methodsAdult patients first admitted for psychosis (n = 126) were retrospectively assessed for early course of illness and characteristics of first help-seeking.

resultsOne-hundred and nine patients reported a prodrome, 58 with CHR symptoms. In patients with an early illness-onset before age 18 (n = 45), duration of both illness and psychosis were elongated, and CHR symptoms more frequent (68.9 vs. 33.3 %) compared to those with adult illness-onset. Only 29 patients reported help-seeking in the prodrome; this was mainly self-initiated, especially in patients with an early illness-onset. After the onset of first psychotic symptoms, help-seeking was mainly initiated by others. State- and age-independently, mental health professionals were the main first point-of-call (54.0 %).

conclusionsAdult first-admission psychosis patients with an early, insidious onset of symptoms before age 18 were more likely to recall CHR symptoms as part of their prodrome. According to current psychosis-risk criteria, these CHR symptoms, in principle, would have allowed the early detection of psychosis. Furthermore, compared to patients with an adult illness-onset, patients with an early illness-onset were also more likely to seek help on their own account. Thus, future awareness strategies to improve CHR detection might be primarily related to young persons and self-perceived subtle symptoms.

Indexed as

Prodromal SymptomsAdolescentAdultEarly DiagnosisFemaleHospitalizationHumansMaleMental RecallMiddle AgedPatient Acceptance of Health CarePatient AdmissionPsychotic DisordersRetrospective StudiesRiskTime FactorsChild and adolescent psychiatryEarly interventionFirst episodeHealth behaviourPsychoses

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.