Evidence map›Paper›PMID 26155477›Full record

ArticleJournal of clinical and diagnostic research : JCDR2015

Prevalence of Enterotoxin Genes and spa Genotypes of Methicillin-resistant Staphylococcus aureus from a Tertiary Care Hospital in China.

Yanmeng Li, Ruike Zhao, Xianfeng Zhang, Qingzhen Han, Xuefeng Qian, Guohao Gu, Jinfang Shi, Jie Xu

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Methicillin-resistant Staphylococcus aureus of the clonal lineage ST5-SCCmecII-t2460 was associated with high mortality in a Wuhan hospital.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Hospital Dissemination ofFrontiers in cellular and infection microbiology · 2017
    Article
  8. Molecular characteristics and virulence gene profiles of Staphylococcus aureus causing bloodstream infection.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yanmeng LiFaculty, Department of Clinical Laboratory, the First Affiliated Hospital of Soochow University , Suzhou, P.R. of China .
Ruike ZhaoFaculty, Department of Clinical Laboratory, the First Affiliated Hospital of Soochow University , Suzhou, P.R. of China .
Xianfeng ZhangFaculty, Department of Clinical Laboratory, the First Affiliated Hospital of Soochow University , Suzhou, P.R. of China .
Qingzhen HanFaculty, Department of Clinical Laboratory, the First Affiliated Hospital of Soochow University , Suzhou, P.R. of China .
Xuefeng QianFaculty, Department of Clinical Laboratory, the First Affiliated Hospital of Soochow University , Suzhou, P.R. of China .
Guohao GuFaculty, Department of Clinical Laboratory, the First Affiliated Hospital of Soochow University , Suzhou, P.R. of China .
Jinfang ShiFaculty, Department of Clinical Laboratory, the First Affiliated Hospital of Soochow University , Suzhou,P.R. of China .
Jie XuFaculty, Department of Clinical Laboratory, the First Affiliated Hospital of Soochow University , Suzhou,P.R. of China .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMethicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen that causes a variety of infections. MRSA has evolved resistance to multiple antibiotics. Genetic background and virulence differs in different geographic regions. The present study was aimed to investigate the prevalence of enterotoxin genes and spa genotypes of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) isolated from a tertiary care hospital of Jiangsu province, China. MATERIALS AND

methodsHA-MRSA isolates from August 2013 to April 2014 at a tertiary care hospital of China were collected. We investigated antimicrobial pattern, spa types, SCCmec types and the presence of 14 virulence genes.

resultsEighty HA-MRSA isolates were collected. Results from SCCmec typing revealed that 73.8% were type II; 13.8% were type III; 12.5% were type V. There were 19 different spa types. Spa type t2460 was the most common (35.0%), followed by t002 (11.3%). CC5 was the predominant MLST CCs type (50%). The most frequent toxin genes were sea, seb, sed, sel, sen and seo (100.0%). None of the investigated isolates carried the sec or tst.

conclusionGenotypic and virulence evaluation of the isolated HA-MRSA revealed that the isolates with CC5 and SCCmec II were the predominant type and highly homological. The virulence profiles mainly existed in the genes of sea, seb, sed, sel, sen, seo and ser. The prevalence of t2460 was an outbreak and the predominant spa type.

Indexed as

seasebsedselsenseosert2460

Identifiers

PMID26155477
PMCPMC4484069

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.