Evidence map›Paper›PMID 26155393›Full record

ArticleOncoimmunology2015

Chronic inflammation in endometriosis and endometriosis-associated ovarian cancer: New roles for the "old" complement pathway.

Robert P Edwards, Xin Huang, Anda M Vlad

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
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  8. Article
  9. Review
  10. Article
  11. The recent progress and therapy in endometriosis-associated ovarian cancer.Journal of the Chinese Medical Association : JCMA · 2020
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Robert P EdwardsDepartment of Obstetrics, Gynecology and Reproductive Sciences; University of Pittsburgh School of Medicine and Magee Women's Research Institute (MWRI) ; Pittsburgh, PA USA ; Magee-Womens Hospital of University of Pittsburgh Medical Center ; Pittsburgh, PA USA.
Xin HuangDepartment of Obstetrics, Gynecology and Reproductive Sciences; University of Pittsburgh School of Medicine and Magee Women's Research Institute (MWRI) ; Pittsburgh, PA USA.
Anda M VladDepartment of Obstetrics, Gynecology and Reproductive Sciences; University of Pittsburgh School of Medicine and Magee Women's Research Institute (MWRI) ; Pittsburgh, PA USA.
Magee-Womens Research Institute · USUniversity of Pittsburgh Medical Center · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
MUC1 Roles in ovarian cancer pathogenesis and immune therapyR01CA163462 · NCI · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI VLAD, ANDA M · 2012 to 2016
$1.4M
NCATS NIH HHS UL1 TR000005NCI NIH HHS R01 CA163462
6 · The paper itself

Abstract

Immune escape is consequential for cancer development. Identifying abnormalities of the immune microenvironment during early carcinogenesis can provide insight into disease pathogenesis and unravel new preventive or therapeutic targets. We recently conducted a comprehensive immune gene expression analysis in endometriosis and endometriosis-associated ovarian cancer and explored new mechanistic roles for the complement pathway.

Indexed as

atypical endometriosiscomplementendometriosisendometriosis-associated ovarian cancer

Identifiers

PMID26155393
PMCPMC4485759
OpenAlexW2239881607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.