Evidence map›Paper›PMID 26155389›Full record

ArticleOncoimmunology2015

Rapid generation of NY-ESO-1-specific CD4

Simone Kayser, Cristina Boβ, Judith Feucht, Kai-Erik Witte, Alexander Scheu, Hans-Jörg Bülow, Stefanie Joachim, Stefan Stevanović, Michael Schumm, Susanne M Rittig and 4 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Cellular immunotherapy in melanoma: the next frontier in cancer treatment.Journal of experimental & clinical cancer research : CR · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Simone KayserUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Cristina BoβDepartment of Dermatology; University Hospital Tübingen ; Tübingen, Germany.
Judith FeuchtUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Kai-Erik WitteUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Alexander ScheuUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Hans-Jörg BülowUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Stefanie JoachimUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Stefan StevanovićInterfaculty Institute for Cell Biology, Department of Immunology, University Tübingen , Tübingen , Germany.
Michael SchummUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Susanne M RittigDepartment of Internal Medicine; University Hospital Tübingen ; Tübingen, Germany.
Peter LangUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Martin RöckenDepartment of Dermatology; University Hospital Tübingen ; Tübingen, Germany.
Rupert HandgretingerUniversity Children's Hospital Tübingen ; Tübingen, Germany.
Tobias FeuchtingerOncology and Stem Cell Transplantation; Dr. von Hauner'sches Kinderspital; Ludwig-Maximilians-University ; Munich, Germany.
University Children's Hospital Tübingen · DEOstschweizer Kinderspital · CHUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-associated antigens such as NY-ESO-1 are expressed in a variety of solid tumors but absent in mature healthy tissues with the exception of germline cells. The immune system anti-cancer attack is mediated by cell lysis or induction of growth arrest through paralysis of tumor cells, the latter of which can be achieved by tumor-specific CD4

Indexed as

ACT, adoptive T cell transferadoptive T-cell transferCD4+ THELPER1 cellscell cycle arrestCTL, cytotoxic T lymphocyteDC, dendritic cellGMP, good manufacturing practiceimmunotherapyNK, natural killerpolyfunctional T cellsTH1, THelper1TIL, tumor-infiltrating lymphocyteTreg, regulatory T cell

Identifiers

PMID26155389
PMCPMC4485840
OpenAlexW2113614442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.