Evidence map›Paper›PMID 26155329›Full record

ReviewJournal of nanotechnology in engineering and medicine2014

The Application of Micropipette Aspiration in Molecular Mechanics of Single Cells.

Lap Man Lee, Allen P Liu

Abstract readReview
In one paragraph

Review in Journal of nanotechnology in engineering and medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. 3DACS biomaterials science & engineering · 2023
    Pooled it
  2. Review
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  12. Cellular and Nuclear Forces: An Overview.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  13. Review
  14. Article
  15. Review
  16. Deformable microlaser force sensing.Light, science & applications · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lap Man LeeDepartment of Mechanical Engineering, University of Michigan , 2350 Hayward Street , Ann Arbor, MI 48109-2125 e-mail:  melmlee@umich.edu.
Allen P LiuDepartment of Mechanical Engineering, Biomedical Engineering, Cell and Molecular Biology Program, Biophysics Program, University of Michigan , 2350 Hayward Street , Ann Arbor, MI 48109-2125 e-mail:  allenliu@umich.edu.

Funding

Building artificial plateletsDP2HL117748 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, ALLEN PO-CHIH · 2012 to 2012
$2.3M
NHLBI NIH HHS DP2 HL117748
6 · The paper itself

Abstract

Micropipette aspiration is arguably the most classical technique in mechanical measurements and manipulations of single cells. Despite its simplicity, micropipette aspiration has been applied to a variety of experimental systems that span different length scales to study cell mechanics, nanoscale molecular mechanisms in single cells, bleb growth, and nucleus dynamics, to name a few. Enabled by micro/nanotechnology, several novel microfluidic devices have been developed recently with better accuracy, sensitivity, and throughput. Further technical advancements of microfluidics-based micropipette aspiration would have broad applications in both fundamental cell mechanics studies and for disease diagnostics.

Identifiers

PMID26155329
PMCPMC4476029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.