Evidence map›Paper›PMID 26154083›Full record

ArticlePloS one2015

Impact of Noncommunicable Disease Multimorbidity on Healthcare Utilisation and Out-Of-Pocket Expenditures in Middle-Income Countries: Cross Sectional Analysis.

John Tayu Lee, Fozia Hamid, Sanghamitra Pati, Rifat Atun, Christopher Millett

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 13 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 13 syntheses or guidelines pooled it, 285 citations in OpenAlex.

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  5. Determinants of multimorbidity in low- and middle-income countries: A systematic review of longitudinal studies and discovery of evidence gaps.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024
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  6. Prevalence of Multimorbidity in the Middle East: A Systematic Review of Observational Studies.International journal of environmental research and public health · 2022
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

John Tayu LeeDepartment of Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom.
Fozia HamidDepartment of Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom.
Sanghamitra PatiIndian Institute of Public Health, Public Health Foundation of India, Bhubaneswar, India.
Rifat AtunDepartment of Global Health and Population, Harvard School of Public Health, Harvard University, Boston, Massachusetts, United States of America.
Christopher MillettDepartment of Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom; Public Health Foundation of India, Gurgaon, India.
Imperial College London · GBPublic Health Foundation of India · INHarvard University · US

Funding

Department of Health IPF-12-05Wellcome Trust
6 · The paper itself

Abstract

backgroundThe burden of non-communicable disease (NCDs) has grown rapidly in low- and middle-income countries (LMICs), where populations are ageing, with rising prevalence of multimorbidity (more than two co-existing chronic conditions) that will significantly increase pressure on already stretched health systems. We assess the impact of NCD multimorbidity on healthcare utilisation and out-of-pocket expenditures in six middle-income countries: China, Ghana, India, Mexico, Russia and South Africa.

methodsSecondary analyses of cross-sectional data from adult participants (>18 years) in the WHO Study on Global Ageing and Adult Health (SAGE) 2007-2010. We used multiple logistic regression to determine socio-demographic correlates of multimorbidity. Association between the number of NCDs and healthcare utilisation as well as out-of-pocket spending was assessed using logistic, negative binominal and log-linear models.

resultsThe prevalence of multimorbidity in the adult population varied from 3.9% in Ghana to 33.6% in Russia. Number of visits to doctors in primary and secondary care rose substantially for persons with increasing numbers of co-existing NCDs. Multimorbidity was associated with more outpatient visits in China (coefficient for number of NCD = 0.56, 95% CI = 0.46, 0.66), a higher likelihood of being hospitalised in India (AOR = 1.59, 95% CI = 1.45, 1.75), higher out-of-pocket expenditures for outpatient visits in India and China, and higher expenditures for hospital visits in Russia. Medicines constituted the largest proportion of out-of-pocket expenditures in persons with multimorbidity (88.3% for outpatient, 55.9% for inpatient visit in China) in most countries.

conclusionMultimorbidity is associated with higher levels of healthcare utilisation and greater financial burden for individuals in middle-income countries. Our study supports the WHO call for universal health insurance and health service coverage in LMICs, particularly for vulnerable groups such as the elderly with multimorbidity.

Indexed as

ComorbidityHealth ExpendituresIncomePatient Acceptance of Health CareAdultCross-Sectional StudiesDemographyDeveloping CountriesDiseaseFemaleHumansMaleOutpatients

Identifiers

PMID26154083
PMCPMC4496037
OpenAlexW2140069888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.