Evidence map›Paper›PMID 26154074›Full record

ReviewCurrent opinion in cardiology2015

Preventing heart failure: the role of physical activity.

Matthew Nayor, Ramachandran S Vasan

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Alcohol consumption and heart failure: a dose-response meta-analysis.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Article
  4. Marital Failure and Subsequent Heart Failure: A Prospective Study.Journal of the American Heart Association · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Active Aging and Smart Public Parks.Geriatrics (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Mechanical overload-induced muscle-derived extracellular vesicles promote adipose tissue lipolysis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  14. Article
  15. Article
  16. Refocusing on the Primary Prevention of Heart Failure.Current treatment options in cardiovascular medicine · 2020
    Article
  17. Article
  18. Article
  19. Conditions Associated with Essential Tremor in Veterans: A Potential Role for Chronic Stress.Tremor and other hyperkinetic movements (New York, N.Y.) · 2018
    Article
  20. Assessment of muscle function using hybrid PET/MRI: comparison ofEuropean journal of nuclear medicine and molecular imaging · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Matthew NayoraFramingham Heart Study, Framingham bDivision of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital cSections of Preventive Medicine & Cardiology, Boston University School of Medicine dDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.
Ramachandran S Vasan
Boston University · USBrigham and Women's Hospital · US

Funding

TRAINING PROGRAM IN CARDIOVASCULAR RESEARCHT32HL007604 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MARK W FEINBERG · 1985 to 2026
$19.0M
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01-HC-25195NHLBI NIH HHS T32 HL007604NHLBI NIH HHS T32-HL007604
6 · The paper itself

Abstract

purpose of reviewHeart failure prevention is an important public health goal. Increased physical activity and exercise may help to prevent heart failure, as they are associated with reduced heart failure incidence and potentially act through a variety of mechanisms to slow disease progression. RECENT

findingsIncreased physical activity, higher cardiorespiratory fitness, and lower sedentary time are associated with reduced heart failure incidence. These associations are consistent for occurrence of heart failure with both preserved and reduced ejection fraction, the common subphenotypes of the condition. Physiologic cardiac and vascular remodeling occurs across the normal range of physical activity in the community, and regular exercise (four to five sessions per week) is necessary to mitigate age-associated reductions in ventricular compliance and cardiac mass. SUMMARY: Greater physical activity, less sedentary time, and improved cardiorespiratory fitness are associated with reductions in heart failure risk. Various mechanisms may explain these findings, including: reducing the prevalence of standard and novel cardiovascular risk factors, inhibiting pathologic cardiovascular remodeling, promoting physiologic remodeling, and improving cardiac, neurohormonal, skeletal muscle, pulmonary, renal, and vascular performance. Future research is needed to elucidate the optimal timing, duration, and modality of physical activity and exercise training necessary to prevent the development of heart failure.

Indexed as

AgingExercise TherapyHeart FailureRisk Reduction BehaviorExercise ToleranceHealth PromotionHumansMotor ActivitySedentary BehaviorStroke VolumeVentricular Remodeling

Identifiers

PMID26154074
PMCPMC4615715
OpenAlexW2396343062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.