Evidence map›Paper›PMID 26153895›Full record

ArticleScientific reports2015

Bio-imaging and Photodynamic Therapy with Tetra Sulphonatophenyl Porphyrin (TSPP)-TiO2 Nanowhiskers: New Approaches in Rheumatoid Arthritis Theranostics.

Chunqiu Zhao, Fawad Ur Rehman, Yanlong Yang, Xiaoqi Li, Dong Zhang, Hui Jiang, Matthias Selke, Xuemei Wang, Chongyang Liu

Abstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  11. Energy Conversion-Based Nanotherapy for Rheumatoid Arthritis Treatment.Frontiers in bioengineering and biotechnology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunqiu ZhaoState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Fawad Ur RehmanState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Yanlong YangDaping Hospital, Third Military Medical University, Chongqing, 400042 P.R. China.
Xiaoqi LiNanJing Foreign Language School, Nanjing 210096, China.
Dong ZhangDepartment of Chemistry and Biochemistry, California State University, Los Angeles, CA 90032, USA.
Hui JiangState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Matthias SelkeDepartment of Chemistry and Biochemistry, California State University, Los Angeles, CA 90032, USA.
Xuemei WangState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Chongyang LiuDaping Hospital, Third Military Medical University, Chongqing, 400042 P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since Rheumatoid arthritis (RA) is one of the major human joint diseases with unknown etiology, the early diagnosis and treatment of RA remains a challenge. In this contribution we have explored the possibility to utilize novel nanocomposites of tetera suplhonatophenyl porphyrin (TSPP) with titanium dioxide (TiO2) nanowhiskers (TP) as effective bio-imaging and photodynamic therapeutic (PDT) agent for RA theranostics. Our observations demonstrate that TP solution PDT have an ameliorating effect on the RA by decreasing significantly the IL-17 and TNF-α level in blood serum and fluorescent imaging could enable us to diagnose the disease in subclinical stages and bio-mark the RA insulted joint.

Indexed as

Diagnostic ImagingNanocompositesPhotochemotherapyPorphyrinsTitaniumAnimalsArthritis, RheumatoidCytokinesDisease Models, AnimalMaleOptical ImagingRatsTheranostic NanomedicineCytokinesPorphyrinsTitaniumtitanium dioxide

Identifiers

PMID26153895
PMCPMC4648397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.