Evidence map›Paper›PMID 26153774›Full record

ReviewSensors (Basel, Switzerland)2015

Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing.

Ti-Hsuan Ku, Tiantian Zhang, Hua Luo, Tony M Yen, Ping-Wei Chen, Yuanyuan Han, Yu-Hwa Lo

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
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  7. Article
  8. Microfluidic Isolation of Aptamers for Intracellular Measurement of Radio-Responsive Proteins.Radiation (Multidisciplinary Digital Publishing Institute) · 2025
    Article
  9. Article
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  11. Review
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  13. Article
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  19. Article
  20. Toward Bioactive Hydrogels: A Tunable Approach via Nucleic Acid-Collagen Complexation.Regenerative engineering and translational medicine · 2024
    Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ti-Hsuan KuDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093-0407, USA. tiku@eng.ucsd.edu.
Tiantian ZhangMaterials Science and Engineering Program, University of California San Diego, La Jolla, CA 92093-0418, USA. tiz022@eng.ucsd.edu.
Hua LuoDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093-0407, USA. luohuabox@gmail.com.
Tony M YenDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093-0412, USA. tmyen@eng.ucsd.edu.
Ping-Wei ChenChemical Engineering Program, University of California San Diego, La Jolla, CA 92093-0448, USA. pingwei320@gmail.com.
Yuanyuan HanDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093-0407, USA. yuh054@ucsd.edu.
Yu-Hwa LoDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093-0407, USA. ylo@ece.ucsd.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection of small molecules or proteins of living cells provides an exceptional opportunity to study genetic variations and functions, cellular behaviors, and various diseases including cancer and microbial infections. Our aim in this review is to give an overview of selected research activities related to nucleic acid-based aptamer techniques that have been reported in the past two decades. Limitations of aptamers and possible approaches to overcome these limitations are also discussed.

Indexed as

Aptamers, NucleotideDNARNASELEX Aptamer TechniqueAnimalsBiotechnologyHumansLiposomesMiceAptamers, NucleotideDNALiposomesRNAaptamerbiomarkersDNAliposomepolymerRNASELEX

Identifiers

PMID26153774
PMCPMC4541879

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.